4 ms·
Especially since mice are not really perfect models for humans. For starters: these mice were "12 to 24 months of age", whereas your typical Alzheimer patient i
by tgv 1y ago
Especially since mice are not really perfect models for humans. For starters: these mice were "12 to 24 months of age", whereas your typical Alzheimer patient is well over 30 times that. The article also links it to amyloid plaques, which is a contested hypothesis that may well have held back Alzheimer research for decades. To be fair, the article seems to look at more mechanisms, but that's well beyond my expertise.
- modeless 1y ago12 to 24 months is old in mouse years. And the article offers a plausible explanation for both why plaques could cause the disease and why clearing them alone might not fix it without lithium supplementation.