Yes, so far my preference has been Tirz. Though cost for Sema is significantly less. It could also be the case that the dose on the Reta I used was too low. I'

Yes, so far my preference has been Tirz. Though cost for Sema is significantly less. It could also be the case that the dose on the Reta I used was too low. I've had a few people mention that they also felt it was fairly weak mg-for-mg, maybe 10mg would have been better. There is a newer formulation, combining Sema with Cagrilintide that is probably the most effective option atm: https://www.nejm.org/doi/full/10.1056/NEJMoa2502081 https://www.nejm.org/doi/full/10.1056/NEJMoa2502081 Price wise, this should give a general idea what Chinese sources sell at: Semaglutide 10mg/vial x 10vials $80 Tirzepatide 10mg/vial x 10vials $72 Retatrutide 10mg/vial x 10vials $130 Cagrilintide 5mg + Semaglutide 5mg 10mg/vial x 10vials $170 (Note that even though Tirz is a few dollars cheaper, 2.5mg Sema = 15mg Tirz or thereabouts)