4 ms·

Just wish there weren’t so many false “studies” promoting benefits of medications that have none. Only slightly better than 1800s snake oil… Would be darkly h

Just wish there weren’t so many false “studies” promoting benefits of medications that have none. Only slightly better than 1800s snake oil… Would be darkly hilarious if the financial cost of semaglutides is what actually contributes to the weight loss. Ozempic is currently the NVIDIA of the pharmaceutical industry.

JumpCrisscross 1y ago
> Only slightly better than 1800s snake oil In the same vein folks were disputing the validity of vitamin C until WWII [1]. There is no shortcut to science. You have to weigh the evidence. Currently, the evidence in favour of GLP-1 agonists is overwhelmingly positive. [1] https://pubmed.ncbi.nlm.nih.gov/23183299/ https://pubmed.ncbi.nlm.nih.gov/23183299/
paulcole 1y ago
> Just wish there weren’t so many false “studies” promoting benefits of medications that have none What’s an example of such a study?
- BobbyTables2 1y ago
  How about “Phenylephrine”? It’s nearly 100 years old and widely used after Pseudoephedrine was more restricted so people couldn’t make meth as easily. Yet, studies not conducted by pharmaceutical manufacturers find it mostly ineffective. Of course, the drug companies publish studies showing it to be effective… Have you ever taken each (not together)? I’ve never heard someone say Phenylephrine did anything for them. Anecdotally, it’s utterly useless for me… I suspect drug companies didn’t want restriction of Pseudoephedrine to decrease sales, so they pushed crap forward to maintain revenue. (Yes, it still isn’t all that hard to get Pseudoephedrine, but one can’t just pick it off the shelf — a significant mental barrier)
PeterStuer 1y ago
It works because people feel 'full' sooner. They do still try to overeat, but feel they can't (and yes, there is habituation as they try day in day out). I'm pretty sure the food industry has been working on a neutralizing agent to add to their preparations since day 1, so the 'victory' wont last. As for longer term consequences? Who knows?
Bud 1y ago
[dead]
shlant 1y ago
it's clear you have a personal bone to pick because your comment is so off base

JumpCrisscross 1y ago

> Only slightly better than 1800s snake oil In the same vein folks were disputing the validity of vitamin C until WWII [1]. There is no shortcut to science. You have to weigh the evidence. Currently, the evidence in favour of GLP-1 agonists is overwhelmingly positive. [1] https://pubmed.ncbi.nlm.nih.gov/23183299/ https://pubmed.ncbi.nlm.nih.gov/23183299/

paulcole 1y ago

> Just wish there weren’t so many false “studies” promoting benefits of medications that have none What’s an example of such a study?

BobbyTables2 1y ago
How about “Phenylephrine”? It’s nearly 100 years old and widely used after Pseudoephedrine was more restricted so people couldn’t make meth as easily. Yet, studies not conducted by pharmaceutical manufacturers find it mostly ineffective. Of course, the drug companies publish studies showing it to be effective… Have you ever taken each (not together)? I’ve never heard someone say Phenylephrine did anything for them. Anecdotally, it’s utterly useless for me… I suspect drug companies didn’t want restriction of Pseudoephedrine to decrease sales, so they pushed crap forward to maintain revenue. (Yes, it still isn’t all that hard to get Pseudoephedrine, but one can’t just pick it off the shelf — a significant mental barrier)

PeterStuer 1y ago

It works because people feel 'full' sooner. They do still try to overeat, but feel they can't (and yes, there is habituation as they try day in day out). I'm pretty sure the food industry has been working on a neutralizing agent to add to their preparations since day 1, so the 'victory' wont last. As for longer term consequences? Who knows?

Bud 1y ago

[dead]

shlant 1y ago

it's clear you have a personal bone to pick because your comment is so off base