Fascinating that you can replace the nucleus of a cell and it keeps working fine, given cells are so complex... I wonder what (if any) setup/precautions are req

Fascinating that you can replace the nucleus of a cell and it keeps working fine, given cells are so complex... I wonder what (if any) setup/precautions are required in the cell biology to make it work. And I wonder if there are genetic conditions in which it can't work (e.g. some sort of mismatch between genes and what's already present in the donor cell)?