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While it is a different category that chromosomal DNA, it is still an essential part of mammalian life. None of use would exist in our current forms without mit
by sidewndr46 1y ago
While it is a different category that chromosomal DNA, it is still an essential part of mammalian life. None of use would exist in our current forms without mitochondria
- pfdietz 1y agoAs I understand it, a human egg has about an equal quantity of nuclear and mitochondrial DNA. The mitochondrial DNA is highly replicated, though (about 100,000 mitochondria, each with ~16600 base pairs of DNA).
- burning_hamster 1y agoI was going to call BS on this one, but after crunching some numbers, if anything this is likely an underestimate. human nuclear genome size (haploid): 3.1 billion bp mitochondrial genome size: 16 000 bp 1 human nuclear genome per egg -> 3.1 billion bp nuclear DNA 100 000 mitochondria, each with 1-10 genomes per mitochondrion [1] -> 1.6-16 billion bp mitochondrial DNA So the ratio of mitochondrial to nuclear DNA in human eggs is on the order of 0.5 to 5. [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4988970/ https://pmc.ncbi.nlm.nih.gov/articles/PMC4988970/
- pfdietz 1y agoThank you for the tidbit that mitochondria each may have multiple copies of that genome.