4 ms·

Cells can exchange mitochondria so in theory it might be possible to flood the body with healthy mitochondria and get them to slowly take over.

• yorwba 1y ago
  I would expect that to activate the immune system. "the unique components of mitochondria, when exposed, reveal their prokaryotic history and are recognized as foreign by innate immune receptors triggering an inflammatory response." https://pmc.ncbi.nlm.nih.gov/articles/PMC6218307/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6218307/ Maybe if you suppress the immune system, introduce working mitochondria, and then stop taking the immunosuppressants, any mitochondria that are still outside cells get cleaned up and the ones that got absorbed are shielded and can do their job.
  • inglor_cz 1y ago
    Maybe we can find some way to deliver mitochondria right into the cells.
• dr_dshiv 1y ago
  Mitochondrial health is definitely going to be a big theme in the coming years.
• type0 1y ago
  > it might be possible to flood the body with healthy mitochondria and get them to slowly take over it's not possible, these are organelles that are too big to be taken up by your cells, unless you can magically teleport them somehow to each cell