3 ms·

>Amanita It's an entirely different class of hallucinogen. I don't have personal experience with it but I have done other dissociative hallucinogens and his ta

by jfyi 1y ago

>Amanita It's an entirely different class of hallucinogen. I don't have personal experience with it but I have done other dissociative hallucinogens and his take is likely largely true (though I wouldn't argue with someone saying they felt euphoria on it). The problem here is it's the entirely wrong mushroom. I can assure any doubters that psilocybin on the other hand has legitimate euphoric effects.

Joel_Mckay 1y ago
The psilocybin containing variety also naturally grow in our yard, and the Amanita is an invasive variety. The "high" people feel is a chemical lobotomy from mild poisoning, and onset of renal failure. Hence why you feel nausea and often erupt out both ends if ingested (especially bad if allergic to a specific fungi.) I asked for 5 citations not sponsored by dealers that he claimed were available, and my post was flagged. To be fair, I would also accept 3 double-blind medical citations of reasonable quality. You can't argue with the irrational, as hitting yourself in the head with a brick also causes similar results. lol =3
- pjerem 1y ago
  https://pubmed.ncbi.nlm.nih.gov/27909164/ https://pubmed.ncbi.nlm.nih.gov/27909164/ https://pubmed.ncbi.nlm.nih.gov/35458717/ https://pubmed.ncbi.nlm.nih.gov/35458717/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12001667 https://pmc.ncbi.nlm.nih.gov/articles/PMC12001667 https://pmc.ncbi.nlm.nih.gov/articles/PMC12030455/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12030455/ None of those publications are sponsored by dealers. There are multiple others which I’m not going to search but I hope now you have starting points, you’ll be curious enough to do further research. > hitting yourself in the head with a brick also causes similar results. That’s false and you aren’t going to find a single paper (funded by anyone) that would conclude this.
  - Joel_Mckay 1y ago
    These studies focused on combined therapy in psychiatry, and do not address the long-term health implications. They do confirm certain strata of the population benefit from the experience, but do not define the underlying mechanism (my concern.) >That’s false and you aren’t going to find a single paper (funded by anyone) that would conclude this. A brick may be too strong for some, but minor brain injury often causes euphoric experiences and personality changes... even if people hop up and down on the spot long enough. Native traditions in Africa have been getting concussion highs that way likely since history began. Incidentally, getting hit with a brick would certainly cause someone to stop ruminating on existential angst for a little while, and euphoric concussions do cause cathartic experiences. lol =3 Notably, the age of surgical and chemical lobotomies were used to treat unruly patients in North America for several decades. Commonly, procedures were applied to treatment resistant criminal psychopaths and countless others with little long-term success. We agree "something" happens (well documented with LSD), but disagree on the safety warnings in your own citations. Which do not clearly address long-term health effects due to the cocktail of other compounds in cancer patients. I am not judging peoples life choices, but we must agree most people that do recreational drugs are not in cancer or psychiatric care. Thank you for the citations, as it cleared up why we differ in opinion on this matter. Best of luck =3
- jfyi 1y ago
  Why don't you show me 5 citations of renal failure from a confirmed psilocybe cubensis in the tens of thousands of years people have been eating them. Or... don't bother, the one you will find is questionable at best if you read past the headline.
  - Joel_Mckay 1y ago
    >Why don't you show me 5 citations of renal failure from a confirmed psilocybe cubensis Mostly, real doctors take "Primum non nocere" very seriously, and do not conflate therapeutic studies as proof organ damage isn't a risk. Fungal infection of those with compromised immune systems is harm. People do experiment on the desperate, but it is rarely ethical gambling with someone's life. The squirrels seem to enjoy their trip, but also seem less invested in trying to justify its safety. May you live an enjoyable life with authentic experiences. Have a glorious day. =3 https://www.youtube.com/watch?v=aNSHZG9blQQ https://www.youtube.com/watch?v=aNSHZG9blQQ
    - jfyi 1y ago
      So no citations then? Seems pretty trollish after making demands for citations just prior. So, just to be clear, you have no evidence of renal failure from psilocybe cubensis?
      - Joel_Mckay 1y ago
        Actually, the citations above already warn 40% of users have neutral to negative side effects, and doesn't get into the consequences of allergic or nausea related symptoms (about 2 of the 5 papers seem of reasonable quality.) So to be clear, cancer patients have a lot of other problems that likely would confound which reported symptoms are related to which medication. Someone with access to the PsycINFO database login could clarify things for sure. If I recall it was a few cases of micro-dosing related organ failure cases that caught my attention. No idea which specific psilocybe mushroom was responsible. The Natives also used Datura, but rolling in your own excrement naked for 2 weeks with severe hallucinations isn't a popular recreational experience for some reason. A few kids die every so often trying to prepare the plant. Have a great day, and stay healthy =3 I must apologize for the low quality data here: https://www.sciencedirect.com/science/article/pii/S2211753918301490 https://www.sciencedirect.com/science/article/pii/S221175391...

by jfyi 1y ago

Joel_Mckay 1y ago

The psilocybin containing variety also naturally grow in our yard, and the Amanita is an invasive variety. The "high" people feel is a chemical lobotomy from mild poisoning, and onset of renal failure. Hence why you feel nausea and often erupt out both ends if ingested (especially bad if allergic to a specific fungi.) I asked for 5 citations not sponsored by dealers that he claimed were available, and my post was flagged. To be fair, I would also accept 3 double-blind medical citations of reasonable quality. You can't argue with the irrational, as hitting yourself in the head with a brick also causes similar results. lol =3

pjerem 1y ago
https://pubmed.ncbi.nlm.nih.gov/27909164/ https://pubmed.ncbi.nlm.nih.gov/27909164/ https://pubmed.ncbi.nlm.nih.gov/35458717/ https://pubmed.ncbi.nlm.nih.gov/35458717/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12001667 https://pmc.ncbi.nlm.nih.gov/articles/PMC12001667 https://pmc.ncbi.nlm.nih.gov/articles/PMC12030455/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12030455/ None of those publications are sponsored by dealers. There are multiple others which I’m not going to search but I hope now you have starting points, you’ll be curious enough to do further research. > hitting yourself in the head with a brick also causes similar results. That’s false and you aren’t going to find a single paper (funded by anyone) that would conclude this.
- Joel_Mckay 1y ago
  These studies focused on combined therapy in psychiatry, and do not address the long-term health implications. They do confirm certain strata of the population benefit from the experience, but do not define the underlying mechanism (my concern.) >That’s false and you aren’t going to find a single paper (funded by anyone) that would conclude this. A brick may be too strong for some, but minor brain injury often causes euphoric experiences and personality changes... even if people hop up and down on the spot long enough. Native traditions in Africa have been getting concussion highs that way likely since history began. Incidentally, getting hit with a brick would certainly cause someone to stop ruminating on existential angst for a little while, and euphoric concussions do cause cathartic experiences. lol =3 Notably, the age of surgical and chemical lobotomies were used to treat unruly patients in North America for several decades. Commonly, procedures were applied to treatment resistant criminal psychopaths and countless others with little long-term success. We agree "something" happens (well documented with LSD), but disagree on the safety warnings in your own citations. Which do not clearly address long-term health effects due to the cocktail of other compounds in cancer patients. I am not judging peoples life choices, but we must agree most people that do recreational drugs are not in cancer or psychiatric care. Thank you for the citations, as it cleared up why we differ in opinion on this matter. Best of luck =3
jfyi 1y ago
Why don't you show me 5 citations of renal failure from a confirmed psilocybe cubensis in the tens of thousands of years people have been eating them. Or... don't bother, the one you will find is questionable at best if you read past the headline.
- Joel_Mckay 1y ago
  >Why don't you show me 5 citations of renal failure from a confirmed psilocybe cubensis Mostly, real doctors take "Primum non nocere" very seriously, and do not conflate therapeutic studies as proof organ damage isn't a risk. Fungal infection of those with compromised immune systems is harm. People do experiment on the desperate, but it is rarely ethical gambling with someone's life. The squirrels seem to enjoy their trip, but also seem less invested in trying to justify its safety. May you live an enjoyable life with authentic experiences. Have a glorious day. =3 https://www.youtube.com/watch?v=aNSHZG9blQQ https://www.youtube.com/watch?v=aNSHZG9blQQ
  - jfyi 1y ago
    So no citations then? Seems pretty trollish after making demands for citations just prior. So, just to be clear, you have no evidence of renal failure from psilocybe cubensis?
    - Joel_Mckay 1y ago
      Actually, the citations above already warn 40% of users have neutral to negative side effects, and doesn't get into the consequences of allergic or nausea related symptoms (about 2 of the 5 papers seem of reasonable quality.) So to be clear, cancer patients have a lot of other problems that likely would confound which reported symptoms are related to which medication. Someone with access to the PsycINFO database login could clarify things for sure. If I recall it was a few cases of micro-dosing related organ failure cases that caught my attention. No idea which specific psilocybe mushroom was responsible. The Natives also used Datura, but rolling in your own excrement naked for 2 weeks with severe hallucinations isn't a popular recreational experience for some reason. A few kids die every so often trying to prepare the plant. Have a great day, and stay healthy =3 I must apologize for the low quality data here: https://www.sciencedirect.com/science/article/pii/S2211753918301490 https://www.sciencedirect.com/science/article/pii/S221175391...