3 ms·

Approved for use means approved for testing on populations.

by zkmon 1y ago

squigz 1y ago
Isn't that how medicine works?
- zkmon 1y ago
  Only for lab mice. Humans require making it clear that they are not being used as lab mice. But often, you see report saying that "After seeing the results for x years of use by populations, we found that it has y side effect which was not known earlier". A doctor literally said this to me last week.
  - Calavar 1y ago
    What alternative process do you propose that will discover all side effects, including those with well under 1% occurence, without human use?
  - squigz 1y ago
    > "After seeing the results for x years of use by populations, we found that it has y side effect which was not known earlier" I would think that any reasonably intelligent adult could think about things for a few moments and come to the realization that... yeah, that's how things work. This is how we progress and learn. We develop, test, use, and learn about things - and if we learn that hey, turns out, this is bad over a long period of time... we change things. And this of course doesn't apply to just medicine - it's just technological progress.
  - wizzwizz4 1y ago
    What's the alternative? "Oh, sorry, we would like to treat your baby's malaria, but that would disregard the baby's inherent dignity: we don't yet know the full side-effect profile up to 3 sigmas." Most indignities are lesser than dying of malaria.
  - standardUser 1y ago
    No one in the US is going to force you to take medication. You are free to die. You are also free to leave.
  - golem14 1y ago
    Some humans might be perfectly willing to be used as lab mice. Those predestined to die soon or have very low quality of life for instance. That's why some advanced cancer patients can get very experimental meds. It gets pretty bad though when others are affected, cf. Thalidomide babies.
1over137 1y ago
As opposed to what?
- parpfish 1y ago
  Probably as opposed to “approved for general use in the population because we’ve passed all of our tests”, which is what I’d assume “approved for use” means
rsynnott 1y ago
Are you taking the stance that no drug should ever be released on the basis that it is impossible for trials to cover literally the entire population? Like, what are you looking for here?

Approved for use means approved for testing on populations.

by zkmon 1y ago

Approved for use means approved for testing on populations.

squigz 1y ago

Isn't that how medicine works?

zkmon 1y ago
Only for lab mice. Humans require making it clear that they are not being used as lab mice. But often, you see report saying that "After seeing the results for x years of use by populations, we found that it has y side effect which was not known earlier". A doctor literally said this to me last week.
- Calavar 1y ago
  What alternative process do you propose that will discover all side effects, including those with well under 1% occurence, without human use?
- squigz 1y ago
  > "After seeing the results for x years of use by populations, we found that it has y side effect which was not known earlier" I would think that any reasonably intelligent adult could think about things for a few moments and come to the realization that... yeah, that's how things work. This is how we progress and learn. We develop, test, use, and learn about things - and if we learn that hey, turns out, this is bad over a long period of time... we change things. And this of course doesn't apply to just medicine - it's just technological progress.
- wizzwizz4 1y ago
  What's the alternative? "Oh, sorry, we would like to treat your baby's malaria, but that would disregard the baby's inherent dignity: we don't yet know the full side-effect profile up to 3 sigmas." Most indignities are lesser than dying of malaria.
- standardUser 1y ago
  No one in the US is going to force you to take medication. You are free to die. You are also free to leave.
- golem14 1y ago
  Some humans might be perfectly willing to be used as lab mice. Those predestined to die soon or have very low quality of life for instance. That's why some advanced cancer patients can get very experimental meds. It gets pretty bad though when others are affected, cf. Thalidomide babies.

1over137 1y ago

As opposed to what?

parpfish 1y ago
Probably as opposed to “approved for general use in the population because we’ve passed all of our tests”, which is what I’d assume “approved for use” means

rsynnott 1y ago

Are you taking the stance that no drug should ever be released on the basis that it is impossible for trials to cover literally the entire population? Like, what are you looking for here?