"Remarkably, a detailed quantum chemical modeling study found that the potencies of several volatile anesthetics were predicted by their binding affinity to del

"Remarkably, a detailed quantum chemical modeling study found that the potencies of several volatile anesthetics were predicted by their binding affinity to delocalized electron sites within the tubulin subunits that make up MTs (Craddock et al. 2015, 2017). These theoretical results essentially reproduce the Meyer–Overton correlation by assuming that anesthesia is primarily mediated by MTs. This cannot be said for any other candidate molecular target. Thus, MTs could be the primary molecular target that mediates the unconsciousness caused by inhalational anesthetics."