While suzetrigine is fascinating and great to see development in that field technically Low‐Dose-Naltrexone (aka LDN) is not an opioid and reduces pain (howev

While suzetrigine is fascinating and great to see development in that field technically Low‐Dose-Naltrexone (aka LDN) is not an opioid and reduces pain (however it does it by modulating opioid receptors so okay I guess it's opioid-related) found more background here https://www.newyorker.com/magazine/2025/06/02/the-radical-development-of-an-entirely-new-painkiller https://www.newyorker.com/magazine/2025/06/02/the-radical-de...