Here's my anecdote. I suffer from psoriasis and psoriatic arthritis. For the most part the psoriasis is not a big deal, it's disfiguring, but only on my legs,

Here's my anecdote. I suffer from psoriasis and psoriatic arthritis. For the most part the psoriasis is not a big deal, it's disfiguring, but only on my legs, and it itches to the point that I'm perfectly capable of scratching long past the point that I'm bleeding. The psoriatic arthritis is another matter, untreated I live somewhere between 5-7 on the pain scale, shaking hands is nerve-wracking (please, no bone crusher handshakes - I do suffer from hand squeezy death) and I can barely walk. On meds I'm basically fine. I use Humira which if I understand correctly is a human monoclonal antibody glued to a receptor that interferes with something to do with T-cells. I.e. it causes a specific immune suppression that massively reduces the process that causes the psoriasis and arthritis symptoms - oh and I'm 100x more likely to get skin cancer. I've been off meds for over 6 months now with very limited impact on my life. All I did was cut out refined sugars and grain from my diet. I discovered this by accident (too lazy to refill my prescription, then realized that I hadn't refilled in ages and yet wasn't in pain) I think that there's a huge load we don't understand in the relationship between inflammation and autoimmune conditions; there are many things that are involved Just my 2¢, I love science so please disregard my anecdotal ramblings