Sure, but I'm talking about where my fingers first reach when taking the device out of my pocket. In that case, I'm grabbing it with my thumb, index finger and

Sure, but I'm talking about where my fingers first reach when taking the device out of my pocket. In that case, I'm grabbing it with my thumb, index finger and middle finger, and since the phone is seated upside down, my thumb reaches the home button before I'm even holding it in my palm. On phones with a fingerprint sensor on the back, I first have to get a full grip, and then I can reach for the sensor. (But it's probably somewhat hand/pocket-specific...)