Some high end gaming motherboards have U.2. If you don't have a U.2 connector, you can use a PCIe adapter card. If you want 16x M.2 slots, you can use two 8x

Some high end gaming motherboards have U.2. If you don't have a U.2 connector, you can use a PCIe adapter card. If you want 16x M.2 slots, you can use two 8x M.2 PCIe carrier cards.