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The event as in the research has occurred, and it was 100% lethal to all mammalian subjects and also the conclusion of the research is that the pathway would be

The event as in the research has occurred, and it was 100% lethal to all mammalian subjects and also the conclusion of the research is that the pathway would be applicable to all mammals. So a lab in fact has created a highly contagious flu virus (far higher than regular flu) through gain of function research which has indeed killed 100% of the subjects which contracted it even if they were only mice.

Jtsummers 1y ago
> So a lab in fact has created a highly contagious flu virus This paper does not appear to support that. They indicate the source was an existing, in the wild virus. >> We isolated an HPAI H5N1 clade 2.3.4.4b virus from wild birds in Korea with 96% E and 4% K at amino acid position 627 of PB2. To investigate the genomic characteristics of this clade regarding mammalian adaptation, we studied the replication and transmission of the H5N1 virus in mice.
- dogma1138 1y ago
  That was the gain of function research. They infected mice with a wild strain that already was pre-positioned to better infect mammals used super high viral loads for that then watched as the mutations which promote mammalian infection evolved and exposed challenge mice to the newly developed strain.