"Dr. Anthony Fauci says chance of coronavirus vaccine being highly effective is ‘not great’" https://www.cnbc.com/2020/08/07/coronavirus-vaccine-dr-fauci-says-

"Dr. Anthony Fauci says chance of coronavirus vaccine being highly effective is ‘not great’" https://www.cnbc.com/2020/08/07/coronavirus-vaccine-dr-fauci-says-chances-of-it-being-highly-effective-is-not-great.html https://www.cnbc.com/2020/08/07/coronavirus-vaccine-dr-fauci... > White House coronavirus advisor Dr. Anthony Fauci that the chances of scientists creating a highly effective vaccine — one that provides 98% or more guaranteed protection — for the virus are slim. > Scientists are hoping for a coronavirus vaccine that is at least 75% effective, but 50% or 60% effective would be acceptable, too, he said. > The FDA has said it would authorize a coronavirus vaccine so long as it is safe and at least 50% effective. From August 2020 before the phase III trials were complete. The Phase III trials dropped in November and showed something like 98% efficacy, but they only followed people for ~3 months, over which time the vaccine actually is that effective. But waning of antibodies and immune escape by the virus severely drags that number down, although prevention of severe disease remains high due to T-cell immunity. People thinking that Fauci said the vaccines would be something like 98% effective against infection and transmission are committing a Mandela effect fallacy. I vividly remember that time period because I was in the camp which expected this coronavirus to behave like other common cold coronaviruses and to periodically reinfect people. I was following that reinfection tracker on BNO news pretty religiously. And I recall vividly that the whole idea that the vaccine would be a magic shot that would instantly shut down the pandemic was something that _people_ wanted desperately to believe, but responsible authorities like Fauci weren't ever actually saying that. The initial Phase III results, combined with the lack of data on reinfections at the time, led to a lot of wildly optimistic beliefs which were not scientifically grounded at all. Then Omicron happened, and it did actually surprise scientists with how much the virus drifted and how much it escaped from existing antibodies. Which was something that nobody really quite predicted, but was in line with general predictions that the coronavirus was never getting eradicated and would eventually become a new seasonal coronavirus. Fauci may have said some things in 2021 that were technically contradicted by Omicron, but there were a lot of wildly optimistic claims after the initial good results of the Phase III trials, and I suspect that any incorrect statements by Fauci were couched in uncertain terms. And nobody during this pandemic was batting for a thousand.