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I wasn't aware that tobacco alternatives added MAO inhibitors to their flavorings - I thought they were basically, in the case of vapes, propylene glycol and ni
by c0nducktr 1y ago
I wasn't aware that tobacco alternatives added MAO inhibitors to their flavorings - I thought they were basically, in the case of vapes, propylene glycol and nicotine + "flavor". Is there evidence that the flavors they're including in these are actually MAOIs?
- cluckindan 1y agoMonoamine oxidase inhibitory activity of flavoured e-cigarette liquids https://www.sciencedirect.com/science/article/abs/pii/S0161813X19301007 https://www.sciencedirect.com/science/article/abs/pii/S01618... Reinforcement and MAO-A inhibition in heated tobacco products: flavor and brand variations https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1515519/full https://www.frontiersin.org/journals/psychiatry/articles/10.... Comparison of monoamine oxidase inhibition by cigarettes and modified risk tobacco products https://www.sciencedirect.com/science/article/pii/S2214750019304925 https://www.sciencedirect.com/science/article/pii/S221475001... There is of course variance depending on the exact flavorants used. For example, menthol and mint flavors don’t inhibit MAO, their activity is towards kappa-opioid agonism (induction of dysphoria).
- c0nducktr 1y agoThanks for this, I'll look into these.