Yes, at higher doses that affect mTORC2 signaling. At a low intermittent dose it is an immune modulator, not an immune suppressor. Much work on parsing the two.

Yes, at higher doses that affect mTORC2 signaling. At a low intermittent dose it is an immune modulator, not an immune suppressor. Much work on parsing the two. But we do not know much about the role of genetic difference in responses ti this drug, so caution is appropriate.