4 ms·
I wonder if there’s a tolerance that builds over time which would also lead to the middle aged / older cohort being less affected than the younger one.
by christophilus 1y ago
I wonder if there’s a tolerance that builds over time which would also lead to the middle aged / older cohort being less affected than the younger one.
- rpdillon 1y agoNot really. Caffeine tolerance builds over a period of days and dissipates over a similar period, roughly 72 hours. The article actually touches on the effect, and it has to do with a reduction of adenosine receptors in middle-aged participants. > “Adenosine receptors naturally decrease with age, reducing caffeine’s ability to block them and improve brain complexity, which may partly explain the reduced effect of caffeine observed in middle-aged participants,” Carrier said.