For me, using a keyboard with more keys around the thumbs and configurable keymaps with layers solves this. I have space, return and esc all easily accessible o

For me, using a keyboard with more keys around the thumbs and configurable keymaps with layers solves this. I have space, return and esc all easily accessible on my thumbs and my most used punctuation across the easily reached keys (such as home row) on a layer, also activated with my thumb. fwiw I use a moonlander but many keyboards could work equally well I'm sure