You can do both. I use to type on 60 key boards using layers but when I switched to using a laptop keyboard it would mess me up as I used caps lock to switch l

You can do both. I use to type on 60 key boards using layers but when I switched to using a laptop keyboard it would mess me up as I used caps lock to switch layers and I had a navigation layer that used hjkl for arrows. So what I changed to a TKL 80 key keyboard for QWERTY and then use Colemak Mod-DH on my split (Cantor Remix). The result is I can type on both due to the context switch. So if I need to use a QWERTY board I am fine. Also my golden rule with split keyboards is I only use open source designs. I don't want to invest time into a layout if the keyboard isn't going to be available in the future.