Kinda... there are GPU instances, but they are targetted towards GPU cluster computing for HPC applications. I suspect that GPU clusters work largely the same

Kinda... there are GPU instances, but they are targetted towards GPU cluster computing for HPC applications. I suspect that GPU clusters work largely the same way that generic/CPU clusters work. You have a cluster manager that dishes jobs out to the worker nodes. The common HPC job scheduler that we use (Torque/PBS) includes support for scheduling jobs that require GPU access. (I assume SGE does as well). Cluster GPU Quadruple Extra Large Instance 22 GB of memory 33.5 EC2 Compute Units (2 x Intel Xeon X5570, quad-core “Nehalem” architecture) 2 x NVIDIA Tesla “Fermi” M2050 GPUs 1690 GB of instance storage 64-bit platform I/O Performance: Very High (10 Gigabit Ethernet) EBS-Optimized Available: No* API name: cg1.4xlarge