3 ms·
There are ~100,000 mitochondria in a human egg cell-- I think that's a pretty tall order.
by reubenswartz 1y ago
There are ~100,000 mitochondria in a human egg cell-- I think that's a pretty tall order.
- aurizon 1y agoYes, I suspect is starts with extra metabolic capability = greater need for the task it is being prepared for. Since women have all their oocytes from an early age - speculating they might mature for fallopian release, and in that maturation mitochondrial proliferation occurs? Alternatively this might occur at puberty with hormonal triggering oocytes in some sequential manner as evolutionary efficiency might be a 'just in time' process?
- koeng 1y agoIt's doable https://www.nature.com/articles/s41467-022-33530-3 https://www.nature.com/articles/s41467-022-33530-3 100,000 x 6kbp == 600 million, or less than 1/5 of our genome. Difficult part is the barcoding bits, but that is not THAT hard.
- reubenswartz 1y agoreading them would be hard enough, but editing them seems pretty darn hard.