3 ms·
Eukaryogenesis is a fascinating topic, and "motherboard" doesn't do it justice. For efficient respiration, you need to have the translation/transcription of ce
by koeng 1y ago
Eukaryogenesis is a fascinating topic, and "motherboard" doesn't do it justice.
For efficient respiration, you need to have the translation/transcription of certain ATP synthase genes near to the membrane for basically JIT-ing them when ready to maintain membrane potential, and hence energy generation. Otherwise, the membrane potential falls apart. This simple need is why there are zero multicellular bacteria and multicellularity evolved 6 times in eukaryotes.
By decoupling the rest of the genome from the JIT bits (ie, mitochondrial DNA), you can scale energy independently of genetic information. So if you need 1000x the energy, you need like 5% more DNA (mitochondrial DNA) instead of 1000x more DNA in your genome.
Some estimates say that our eukaryotic genes are in charge of 5000x more energy than the equivalent bacterial gene. Hence, our genomes can inflate that much and its fine. And they have. All that inflation lets us have bullshit hang around in our genome, and hey, sometimes evolution figures out something to do with all that bullshit. We evolved 1000x more complexity than bacteria because we decoupled the performance code from the rest of the code.
- kridsdale1 1y agoI learned some new concepts from this post. You are hereby granted one hyper-upvote.
- ag_rin 1y agoThis is a super interesting set of thoughts. Do you have any further reading that helped form this conclusion or is your intuition just that cool.
- koeng 1y agoCheck this out - https://sci-hub.ru/https://doi.org/10.1038/nature09486 https://sci-hub.ru/https://doi.org/10.1038/nature09486