5 ms·
Okay, I'll bite: Who then was the first patient of any age to have a custom gene-editing treatment?
by autoexec 1y ago
Okay, I'll bite: Who then was the first patient of any age to have a custom gene-editing treatment?
- sigzero 1y ago[flagged]
- jfarlow 1y agoThis is an AI-generated response, and is inaccurate. That was one of the first cases of _germline_ gene editing using CRISPR - NOT "the first instance of gene editing." There have been quite a few other genetic editing tools that predate CRISPR, and there have been other edits using CRISPR that were not of the entire human's genome.
- deleted 1y ago[deleted]
- shermantanktop 1y agoAh yes, the "neutral" tone of AI generated content. "significant controversy and ethical concerns," sure.
- sigzero 1y agoThere are always those concerns.
- roywiggins 1y agoThat is not accurate, attempts at gene therapy in humans go back further than that. https://www.whatisbiotechnology.org/index.php/science/summary/gene-therapy/ https://www.whatisbiotechnology.org/index.php/science/summar...
- namuol 1y agoI know of at least one YouTuber who took a homemade treatment that alerted his GI system DNA to produce lactase so he could eat pizza again: https://youtu.be/J3FcbFqSoQY https://youtu.be/J3FcbFqSoQY
- codeulike 1y agoThat's not gene editing, but you could call it a gene therapy - he's introducing new fragments of DNA/RNA into his cells which then just float around and cause the right enzyme get made. Sometimes called upregulation. This is different to actually editing the existing DNA in the cell.
- namuol 1y agoGood point - to be honest I didn’t realize the difference which is very significant from a treatment perspective.
- agos 1y agoI remember six kids treated with a HIV retrovirus based therapy in 2013 in Italy