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If the epigenetic drift theory of aging is correct, it's because when the jellyfish becomes a polyp again its epigenome is reset to factory defaults, erasing th
by fallingfrog 1y ago
If the epigenetic drift theory of aging is correct, it's because when the jellyfish becomes a polyp again its epigenome is reset to factory defaults, erasing the effects of aging.
According to this theory, the reason the epigenome accumulates damage is because while the dna strand is static through the life of the organism, and therefore has all sorts of error correction mechanisms, the epigenome changes on a per-cell level as the organism grows according to hormonal signals and so on. That's how a nerve cell and a muscle cell can have the same dna strand but act almost as if they are from totally different species. Therefore it has to be flexible and can't be error checked in the same robust way. So aging is a consequence of multicellular life cycles.