The only way to compete is to sell used stuff or make your own products (or provide a marketplace for those things). Well, there are other markets that fall ou

The only way to compete is to sell used stuff or make your own products (or provide a marketplace for those things). Well, there are other markets that fall outside this... For example, at Quartzy we are working in the life-sciences market. There are multi-billion dollar incumbents like Thermo Fisher, VWR, EMD, Sigma and scores of others but the game is different because you are distributing stuff that could be hazardous/require ice/could be radioactive etc. Amazon's warehouses are not equipped (as far as I know) to handle such products. So one can target markets that have seen no innovation in the last 15 years where Amazon does not have an advantage... Amazon is getting into lab supplies (glassware etc) but a problem here is that Amazon likes to have one-price and all the manufacturers play a game where there is a list price and a special price at your institution. This is a game for some reason that Amazon does not want to play so in general for a couple of reasons they are locked out for a large fraction of the huge life-sciences market. Wonder if there are other markets like this out there?