3 ms·

Hard to know what to make of this when the types of detergent are not disclosed. I recall in 2022, Oxyclean was recommended for destroying MPOX virions.

gpm 2y ago
For what it's worth the supplemental methods file has this to say about the detergents selected > Two commonly used UK washing detergents were selected for the assay: a non-biological liquid detergent (15-30%:Anionic surfactants; 5-15%:nonionic surfactants; <5%:phosphonate, perfume, soap, optical brighteners, methylisothiazolinone, octylisothiazolinone) and a non-biological powder detergent (5-15%: oxygen-based bleaching agents, anionic surfactants; <5%: nonionic surfactants, polycarboxylates, soap, perfume, phosphonates, optical brighteners, zeolites) This doesn't really mean anything to me, but maybe it means something to you? In some sense I think the real takeaway from the study is "we shouldn't be having healthcare workers wash their own patient/pathogen facing uniforms", and that takeaway seems robust against the hypothesis that only some detergents would solve the problem. As a population we can be sure that some of the healthcare workers are going to use the detergents that don't solve the problem.
- tehjoker 2y ago
  The second one sounds similar to oxyclean.
- twic 2y ago
  Interesting, the materials and methods says: > Each wash cycle was performed with either biological (14g per kilogram of fabric) or non-biological detergents (20g per wash). But your quoted passage describes two non-biological detergents. So did they use a biological detergent or not? Anyway, the first one sounds like Persil liquid: https://www.ocado.com/products/persil-laundry-washing-liquid-detergent-non-bio-53-washes-524869011 https://www.ocado.com/products/persil-laundry-washing-liquid... > 15-30%: Anionic surfactants. 5-15%: Nonionic surfactants. <5%: Perfume, Phosphonates, Soap, Optical brighteners, Methylisothiazolinone, Octylisothiazolinone And the second one sounds like Persil powder: https://www.ocado.com/products/persil-fabric-cleaning-washing-powder-non-bio-77-washes-578954011 https://www.ocado.com/products/persil-fabric-cleaning-washin... > 5-15%: Oxygen-based bleaching agents, Anionic surfactants. <5% Nonionic surfactants, Polycarboxylates, Soap, Perfume, Optical brighteners, Zeolites, Tetramethyl acetyloctahydronaphthelenes Not quite the same, but similar. Both are perfectly normal brand-name household laundry detergents.
  - gpm 2y ago
    > But your quoted passage describes two non-biological detergents. So did they use a biological detergent or not? It depends on what experiment in the paper you are looking at. The supplemental section is addressing the "Laundry detergent tolerance induction assay" (a heading you can ctrl-f for) where they only used the non-biological detergent, "as biological detergent contains enzymes and other potentially disruptive components that may influence the assay". If you go to the results section you will see results for both the biological and non-biological detergent under "Decontamination efficacy of domestic laundry machines" and so on. I didn't see anything specifying what biological detergents were used.

gpm 2y ago

For what it's worth the supplemental methods file has this to say about the detergents selected > Two commonly used UK washing detergents were selected for the assay: a non-biological liquid detergent (15-30%:Anionic surfactants; 5-15%:nonionic surfactants; <5%:phosphonate, perfume, soap, optical brighteners, methylisothiazolinone, octylisothiazolinone) and a non-biological powder detergent (5-15%: oxygen-based bleaching agents, anionic surfactants; <5%: nonionic surfactants, polycarboxylates, soap, perfume, phosphonates, optical brighteners, zeolites) This doesn't really mean anything to me, but maybe it means something to you? In some sense I think the real takeaway from the study is "we shouldn't be having healthcare workers wash their own patient/pathogen facing uniforms", and that takeaway seems robust against the hypothesis that only some detergents would solve the problem. As a population we can be sure that some of the healthcare workers are going to use the detergents that don't solve the problem.

tehjoker 2y ago
The second one sounds similar to oxyclean.
twic 2y ago
Interesting, the materials and methods says: > Each wash cycle was performed with either biological (14g per kilogram of fabric) or non-biological detergents (20g per wash). But your quoted passage describes two non-biological detergents. So did they use a biological detergent or not? Anyway, the first one sounds like Persil liquid: https://www.ocado.com/products/persil-laundry-washing-liquid-detergent-non-bio-53-washes-524869011 https://www.ocado.com/products/persil-laundry-washing-liquid... > 15-30%: Anionic surfactants. 5-15%: Nonionic surfactants. <5%: Perfume, Phosphonates, Soap, Optical brighteners, Methylisothiazolinone, Octylisothiazolinone And the second one sounds like Persil powder: https://www.ocado.com/products/persil-fabric-cleaning-washing-powder-non-bio-77-washes-578954011 https://www.ocado.com/products/persil-fabric-cleaning-washin... > 5-15%: Oxygen-based bleaching agents, Anionic surfactants. <5% Nonionic surfactants, Polycarboxylates, Soap, Perfume, Optical brighteners, Zeolites, Tetramethyl acetyloctahydronaphthelenes Not quite the same, but similar. Both are perfectly normal brand-name household laundry detergents.
- gpm 2y ago
  > But your quoted passage describes two non-biological detergents. So did they use a biological detergent or not? It depends on what experiment in the paper you are looking at. The supplemental section is addressing the "Laundry detergent tolerance induction assay" (a heading you can ctrl-f for) where they only used the non-biological detergent, "as biological detergent contains enzymes and other potentially disruptive components that may influence the assay". If you go to the results section you will see results for both the biological and non-biological detergent under "Decontamination efficacy of domestic laundry machines" and so on. I didn't see anything specifying what biological detergents were used.