> AFAICT there are no approved drugs blocking EPO receptors and no drugs to reduce EPO Such receptors have a protein structure definitive for them, so a bespok

> AFAICT there are no approved drugs blocking EPO receptors and no drugs to reduce EPO Such receptors have a protein structure definitive for them, so a bespoke RNA (mRNA) therapy might be a means of generating receptor blockers? Edit: looks like this applicable. two interesting articles... https://pubmed.ncbi.nlm.nih.gov/28629523/ https://pubmed.ncbi.nlm.nih.gov/28629523/ https://www.genengnews.com/topics/cancer/blocking-erythropoietin-signaling-in-mice-converts-liver-tumors-into-immunotherapy-responders/ https://www.genengnews.com/topics/cancer/blocking-erythropoi...