5 ms·
This is about a specific condition but it shouldn't be a surprise to anyone really. I remember when there was a huge push on reddit and everywhere to decrimina
by mrtksn 2y ago
This is about a specific condition but it shouldn't be a surprise to anyone really.
I remember when there was a huge push on reddit and everywhere to decriminalize and later legalize marijuana and I was a supporter of the movement and still support it but only as a liberty principle. After getting into smoking it regularly in college I had the chance to meet long time users and without exception all of them had cognitive issues. One day I was late for a party and everyone was high when I arrived and I realized that I simply can't stand them because everything they said was the lowest IQ stuff I ever heard and they were pretending that its creative. Quit the thing and never looked back.
Stick to the alcohol and drink within the culture of it and you will be fine. It is bad for your body even at small quantities but at least you keep your mind intact and alcohol actually enhances the creativity by lowering your guard and not interfering with your intelligence. The culture part is important, binge drinking can be fun at college at times but the culture I'm referring is the culture where alcohol is being consumed socially together with some food or at event. Avoid drinking alone and other high risk activities associated with drinking.
I keep reading about how alcohol consumption is dropping, pubs are closing and this makes me sad because I see how young people lock themselves into apartments and smoke weed all day. I don't believe that anything good comes out of it, no wonder the loneliness epidemic is destroying the world.
It's a very unpopular opinion and in some countries drinking only means getting smashed but trust me, there's another way. With weed, there's no another way.
Anyway, here's something fun to watch on the topic: https://www.youtube.com/watch?v=VTSCppeFzX4 https://www.youtube.com/watch?v=VTSCppeFzX4
- pedrogpimenta 2y agoThat's just, like, your experience, man. I smoke weed socially. And know many that drink alone at home. Don't just, like, generalize, man.
- pinoy420 2y ago[dead]
- deleted 2y ago[deleted]
- int_19h 2y agoIn my experience, the very same people who claim that they drink in moderation and retain full control are exactly the ones that tend to be unpleasant to be around when drunk.
- hobs 2y agoPretty weird that "go drink yourself to death instead" is the top comment on HN. Stinkin Thinking is what my grandmother used to say about people making decisions on booze, its not some magic defense against neurodegenerative stuff. Nobody should be defending some dumb stoners, but the idea that you can protect your mental health by hard drinking is deeply unsupported by science. https://pmc.ncbi.nlm.nih.gov/articles/PMC7488355/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7488355/ Alcohol use disorder (AUD) has been associated with neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. Prolonged excessive alcohol intake contributes to increased production of reactive oxygen species that triggers neuroimmune response and cellular apoptosis and necrosis via lipid peroxidation, mitochondrial, protein or DNA damage. Long term binge alcohol consumption also upregulates glutamate receptors, glucocorticoids and reduces reuptake of glutamate in the central nervous system, resulting in glutamate excitotoxicity, and eventually mitochondrial injury and cell death. In this review, we delineate the following principles in alcohol-induced neurodegeneration: (1) alcohol-induced oxidative stress, (2) neuroimmune response toward increased oxidants and lipopolysaccharide, (3) glutamate excitotoxicity and cell injury, and (4) interplay between oxidative stress, neuroimmune response and excitotoxicity leading to neurodegeneration and (5) potential chronic alcohol intake-induced development of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease.
- mrtksn 2y agoYes, alcohol is very bad if you drink it wrong. The core of what I say is that, drink it the right way(don't drink hard regularly, never drink alone) or don't drink it(you don't have to drink but you will be missing out). Don't smoke anything.
- Mistletoe 2y agoThe new science says there is no safe level of alcohol and that it is just a straight up poison for your body. Previous studies were flawed. https://www.who.int/europe/news/item/04-01-2023-no-level-of-alcohol-consumption-is-safe-for-our-health https://www.who.int/europe/news/item/04-01-2023-no-level-of-...
- soupfordummies 2y agoI had to read it three times to realize "the criminal eyes" meant "decriminalize"
- sceptic123 2y ago> One day I was late for a party and everyone was high when I arrived and I realized that I simply can't stand them because everything they said was the lowest IQ stuff I ever heard and they were pretending that its creative. And that never happened with alcohol?
- mrtksn 2y agoIt happens when someone is very drunk. People socializing with alcohol are still a nice company to people who don't drink. The nice thing about alcohol is the dynamic range of its effects. The bad stuff start after the "tipsy" stage and even after that there's quite a bit of way to go until things become a problem.
- sceptic123 2y agoI would be surprised if the people who don't drink agreed with you here. And let's make sure we ignore the links between alcohol use and violence here too.
- mrtksn 2y agoDefinitely don't abuse alcohol, that's very bad for you and the society. Learn how to drink properly
- apercu 2y ago>Learn how to drink properly ~10% of the population simply cannot. I'd argue it's a lot higher of a percentage in places like here in Wisconsin.
- sceptic123 2y agoWhy doesn't that same thing apply to recreational drug use? And the argument for legalisation is that it makes that use much safer.
- 2y ago
- Smithalicious 2y agoWow, I didn't actually think weed could give someone brain damage, but I guess I've just been conclusively proven wrong!
- herculity275 2y agoI see a version of this reply every time somebody mentions that cannabis is not entirely harmless. Without getting into the weeds (lol) of what is and is not brain damage, surely you can recognize that habitually blazing extremely potent strains of a hallucinogenic plant is not harm-free?
- AngryData 2y agoWell harm has to be defined because different people use it in different ways. Would I say it cannot cause mental changes that can be negative? Of course not, plenty of people don't smoke just because of the anxiety they get from it or other things. But classifying people who smoke as stupid or brain damaged is an entirely different thing and there is very little evidence for that. Social and ideological changes that hallucinogens can cause in general are not simply good versus bad. And there is no link anywhere that makes hallucinating itself cause brain damage, there are tons of ways for people to hallucinate that don't cause brain damage so I don't know why you would automatically assume any hallucinogen is assuredly doing damage.
- Ancapistani 2y agoI hate to be that person, but neither the article nor the study makes that claim. All we know is that people who visit the ER or who are hospitalized "for cannabis use" (not defined in the abstract; full text is behind a paywall) end up with dementia at a higher rate. That does not mean cannabis caused it. They've accounted for many confounding factors, but you can't account for all of them. Off the top of my head, perhaps people who are in the very early stages of dementia do not tolerate THC as well? Maybe their emotional regulatory ability declines before diagnosis, and they're therefore less able to bring themselves down if they experience anxiety.
- Spacemolte 2y agoI came to the same conclusion after meeting old friends who had smoked a lot.
- cassepipe 2y agoI was in a group of friends and I think one of the guys appreciated me and tried to get closer to me. Once he stopped by the house and we spent the evening talking, me drinking and him smoking. Having to wait through his long silences where he tried to form coherent thoughts but always ending up in unfinished sentences was an excruciating experience. That friendship did not work out.
- roenxi 2y ago> Stick to the alcohol and drink within the culture of it and you will be fine. The median marijuana user is probably also fine in similar circumstances. This study is talking about "someone who has an emergency room visit or hospitalization due to cannabis" - which I assume isn't the normal experience. And heavy users probably do have a raft of problems but unless we have statistics to break out its probably comparable to the horrors of the serious alcoholics (I had a neighbour once who was vegetabalised after a drunken pub fight - nobody will talk me out of blaming the grog for that one). Although I would echo the general theme of your post which is that if someone is worried about their health and wellbeing, maybe avoid the drugs. Although I'd go further and say avoid the alcohol too. Humans have been dealing in drugs and alcohol for millennia at this point. They're not good for you in large doses and the benefits in small doses are questionable (which, given the millennia thing, suggests they may not be there). There is a tactical "benefit" in convincing people to do silly things and they make individuals feel good for a while.
- neogodless 2y agoSocially, I agree with this comment. I got very bored at parties where everyone was getting high. Scientifically, apparently alcohol is worse for your brain. From the study[0]: > Individuals with acute care due to cannabis use were at lower risk than those with acute care due to alcohol use (aHR, 0.69; 95% CI, 0.62-0.76). Personally, someone very close to me had an acute emergency room visit about 5 years ago due to what we can only assume was a poorly dosed edible, and/or a newly developed severe allergy. Fingers crossed they do not develop dementia. (Per the study, looks like odds are 1 in 20 for those that hit the ER.) [0] https://pubmed.ncbi.nlm.nih.gov/40227745/ https://pubmed.ncbi.nlm.nih.gov/40227745/
- mtlmtlmtlmtl 2y ago>With weed, there's no another way Based on what, your personal experience talking to stoners in college? Plenty of people smoke socially, and among people who smoke cannabis, only a small fraction "lock themselves into apartments and smoke weed all day". In fact, that fraction is much smaller than the fraction of people who drink alcohol who lock themselves in their apartments drinking all day. And I don't know if you've spent any time with those people, but they all have cognitive issues too. As do people who do speed all day. As do people who do heroin all day. Cannabis can be a wonderful social drug, as can amphetamine or cocaine, and I'm sure even opioids, though I don't touch those because I have significant genetic risk for opioid addiction. I don't think judging a drug by its most addicted users is fair. Especially since you're doing that for weed, and then comparing that to the most reasonable alcohol users. All that being said, I absolutely agree that cannabis is not good for you in large quantities. It's absolutely bad for cognitive ability, working memory, and long term memory when used chronically. But the only people I've met who would disagree with that are cannabis addicts, and usually young ones at that(the older ones tend to figure it out unless they stay stoned for their entire lives, which does happen). Most people I talk to are well aware of these things. And at least from my own experience, these effects will generally pass once you cut down.
- swed420 2y ago> Based on what, your personal experience talking to stoners in college? Plenty of people smoke socially Yep. And plenty smoke privately, too. People see the public spectacles and incorrectly conclude it as wholly representative. Many professionals use cannabis but choose to not advertise it since misinformation is still so rampant, originating from the "Reefer Madness" propaganda days. The tradeoff of potential career damage just isn't worth it. Carl Sagan understood this, among many others: https://bigthink.com/health/carl-sagan-on-smoking-marijuana/ https://bigthink.com/health/carl-sagan-on-smoking-marijuana/
- AngryData 2y agoWhat do you mean there is no other way with weed? You don't have to go full Cheech and Chong with smoking. Your experience doesn't match mine at all, 7/10 of the most brilliant people I know, half of which are mechanical or electrical engineers, smoke weed regularly. To me your comment reads like government propaganda from 60 years ago.
- mrtksn 2y agoOkay, how does it look like to be slightly high? With alcohol stages are something like this: 1) First it makes you relaxed. With the help of the music and the company you start feeling integrated. Thats usually within the first hour of social drinking. 2) Later you usually feel liberated, at this stage your personality and emotional state becomes exposed. You can become more friendly, more talkative or if you are not well you can start opening up about it and even cry a bit. You feel a bit tipsy but this is not the dominant feeling. It depends, but the gist is that you lower your guard. This is the stage where most benefits of drinking is. Usually can be maintained for a few hours by keep drinking slowly. 3) Next the effect of alcohol start becoming a bit more pronounced, you feel funny and you might start having motor skill issues. This is the stage you better stop. There's nothing good beyond this. Ideally this is at the end of the night and you are headed home. 4) Then you actually become drunk, you start slurring when talking. Your motor skills are severely impacted and emotional issues may arise and you can do things you will regret later. This usually happens very late at the hight of drinking. 5) The last stage is when you are blackout level drunk and don't remember much tomorrow. At this stage you need to have someone to look after you. You can be a danger to yourself and people around you. It happens when you push it. How does the weed smoking look like? Where the social smoking fits in this?
- jermaustin1 2y agoA lower dose strain, or a strain with higher CBD:THC ratio would keep you basically at stage 1/2 all night. The thing about weed is that, if you are getting it legally at a dispensary in a state with strict and enforced testing laws (so not CA), you can get yourself a nice low strength sativa/hybrid while avoiding anything with high CBN (that's the couching chem). You will be buzzed off a hit or two, and you just take another hit every 30-60 minutes or so (everyone's mileage WILL vary). It is just like staying buzzed on alcohol is approximately 1 beer/hr (according to the ancient wisdom of older brother's since the dawn of time). All drugs have their tolerances and and all drugs have people who abuse them and people who are "allergic" to them and should avoid them at all cost.
- apercu 2y agoMy anecdotal experience is very different than yours. People on alcohol have issues managing their emotions and impulses, and a lot of men get aggressive and violet - and most of the people that I encounter that consume cannabis you'd never know. Now, that doesn't cover every case, I run in to people who vape cannabis all the time, and they seem to have some emotional effects from that, but if someone is going to abuse a substance, I'd much prefer that was cannabis. Alcohol is a poison, look at the biology at work when your body processes. Re: cannabis, smoking anything is unhealthy, so maybe don't smoke.
- carlmr 2y ago>Stick to the alcohol and drink within the culture of it and you will be fine. It is bad for your body even at small quantities but at least you keep your mind intact Even moderate consumption of alcohol leads to structural and volumetric brain changes: https://www.nature.com/articles/s41467-022-28735-5 https://www.nature.com/articles/s41467-022-28735-5
- cassepipe 2y agoI am pretty sure your vision of alcohol "being fine" at low doses is quite simplistic and you are avoiding taking into account people's differences in your comments but I personally don't like weed much and also think alcohol is the best drug. And it's pleasant to read a wall of text on why it is indeed the best drug. Thank you for choosing to die on this hill. I will remember you, comrade.
- sitzkrieg 2y agoalcohol is great for destroying your body unlike weed. and being obnoxious
- dzhiurgis 2y agoI'm in late 30s and finally gave up booze after something like 25 years of drinking. I still smoke a tiny bit of marijuana every few weeks. I do notice it causes mood swings next few days. Ironically it is prescribed for anxiety. Alcohol depression took nearly a month to clear. I'm sad I can't drink socially, but I still go thru a ton of zero alcohol beer. I'll change the strain from indica to sativa just for a check. Occasionally I do enjoy silliness it brings that makes me wanna play with my kids. Or have some superficially deep thinking while riding bike. Otherwise I'll likely stop too.