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Most people who go on Testosterone can go off it just fine. Here's a random study: >Ever since that study, testosterone has undergone extensive clinical trial

by treis 2y ago

Most people who go on Testosterone can go off it just fine. Here's a random study: >Ever since that study, testosterone has undergone extensive clinical trials as a hormonal method of male contraception and many have found testosterone to be efficacious, reversible and safe with minimal short-term side effects https://pmc.ncbi.nlm.nih.gov/articles/PMC6305868/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6305868/ It's not super reliable but it's also easily testable if it's working or not.

AstralStorm 2y ago
It also causes temporary shrinkage in the high overdose needed for any reliability, as opposed to normal dosage.
margalabargala 2y ago
To be clear, the snippet you quoted is your study summarizing the claims of other studies which are among the cohort analyzed. Let's quote the short, succinct conclusion of the study you picked: > Testosterone therapy is a contraceptive, albeit a poor one. Men of reproductive age with low testosterone should be counseled on the adverse effects of TRT on fertility. Obtaining a semen analysis and possible cryopreservation of sperm should be offered if TRT is prescribed to men interested in preserving fertility. Options such as clomiphene citrate and hCG along with a referral to a reproductive urologist should be considered to naturally increase testosterone levels in those men with low testosterone who want to avoid TRT. Whether a contraceptive that is sufficiently irreversible that men using it are advised to freeze sperm if they ever want kids should be considered "reversible" is left as an exercise to the reader.
- treis 2y ago
  You're misunderstanding what they're saying here. They are saying TRT will have an impact on fertility while they are on TRT. The prospects for when they go off TRT are fine: >If a patient currently desires fertility, TRT should be avoided or discontinued immediately. A semen analyses should be performed if the patient has discontinued TRT. Azoospermia or severe oligospermia may be seen in these patients, but most men should return to baseline semen analyses in 6 to 9 months after cessation of TRT [13,14,15]. A 2006 integrated analysis showed that 90% of patients were expected to return to baseline sperm concentration values 12 months after cessation of treatment and 100% after 24 months [50].
  - margalabargala 2y ago
    I'm not misunderstandings, you are conflating several different things: TRT, testosterone as a contraceptive, and testosterone as a body building steroid. TRT is a very low dose of testosterone, used to supplement the body when it doesn't produce enough. It is reversible as you say, and has a negative effect on fertility but not enough to be reliably effective as a contraceptive at TRT dosages. Testosterone as a contraceptive or steroid is a far higher dose. This is the one that has permanent effects.

by treis 2y ago

AstralStorm 2y ago

It also causes temporary shrinkage in the high overdose needed for any reliability, as opposed to normal dosage.

margalabargala 2y ago

To be clear, the snippet you quoted is your study summarizing the claims of other studies which are among the cohort analyzed. Let's quote the short, succinct conclusion of the study you picked: > Testosterone therapy is a contraceptive, albeit a poor one. Men of reproductive age with low testosterone should be counseled on the adverse effects of TRT on fertility. Obtaining a semen analysis and possible cryopreservation of sperm should be offered if TRT is prescribed to men interested in preserving fertility. Options such as clomiphene citrate and hCG along with a referral to a reproductive urologist should be considered to naturally increase testosterone levels in those men with low testosterone who want to avoid TRT. Whether a contraceptive that is sufficiently irreversible that men using it are advised to freeze sperm if they ever want kids should be considered "reversible" is left as an exercise to the reader.

treis 2y ago
You're misunderstanding what they're saying here. They are saying TRT will have an impact on fertility while they are on TRT. The prospects for when they go off TRT are fine: >If a patient currently desires fertility, TRT should be avoided or discontinued immediately. A semen analyses should be performed if the patient has discontinued TRT. Azoospermia or severe oligospermia may be seen in these patients, but most men should return to baseline semen analyses in 6 to 9 months after cessation of TRT [13,14,15]. A 2006 integrated analysis showed that 90% of patients were expected to return to baseline sperm concentration values 12 months after cessation of treatment and 100% after 24 months [50].
- margalabargala 2y ago
  I'm not misunderstandings, you are conflating several different things: TRT, testosterone as a contraceptive, and testosterone as a body building steroid. TRT is a very low dose of testosterone, used to supplement the body when it doesn't produce enough. It is reversible as you say, and has a negative effect on fertility but not enough to be reliably effective as a contraceptive at TRT dosages. Testosterone as a contraceptive or steroid is a far higher dose. This is the one that has permanent effects.