4 ms·

Closer to 90%, and generally the side effects are a bit annoying too. Circulatory ones. Sometimes even to floppy. (Like 1% dosage dependent) Plus the thing doe

Closer to 90%, and generally the side effects are a bit annoying too. Circulatory ones. Sometimes even to floppy. (Like 1% dosage dependent) Plus the thing does not stop the drip so you do have to pull out sooner rather than later or else. It does not stop sperm production. Also dry ones tend to result. They're sometimes uncomfortable. Tamsulosin is I believe the modern one but all of them are for long term. Probably least side effects. Otherwise if taken as a single dose fresh, side effects like orthostatic hypotension are vastly increased.

johnisgood 1y ago
Circulatory side effects like dizziness or orthostatic hypotension do occur, though they tend to be mild and dose-dependent. You're right that it doesn't stop sperm production, just emission. As for "the drip"; that's pre-ejaculate, which doesn't contain sperm inherently, but can pick up residual sperm in the urethra from a prior ejaculation. And that's true, anejaculatory orgasms can feel strange or less satisfying for some, but it is not universal. > Otherwise if taken as a single dose fresh, side effects like orthostatic hypotension are vastly increased. That is true. Edit: I / We will have to research the side-effect profile and mechanisms of the mentioned pill (in the submission). I have not yet done so. They mention no side-effects but it might be too early to tell.
- cstrahan 1y ago
  > You're right that it doesn't stop sperm production, just emission. As for "the drip"; that's pre-ejaculate, which doesn't contain sperm inherently, but can pick up residual sperm in the urethra from a prior ejaculation. I’d like to stress that point a bit. I had a vasectomy about a year ago, and being the weirdo that I am, I figured I’d see how much sperm remained in my ejaculate (and for how long) after the procedure. I waited maybe two or three days after the procedure, and then for the next three days, I’d collect three samples per day and take a look under my microscope. In the first four or five samples, the swimmers were swimming hard. Told my brother (who had been trying for a kid for a couple years, and had observed his own samples trying correlate diet and other factors to improved motility) about the straight laser beams I was seeing in the scope — he nearly had a fit when I described how long it took them to go from one side of the slide to the other under the given magnification. It was the ninth sample when there were very few observable sperm, and what remained looked kinda drunk and unmotivated. All of that to say: if you’re going to get a vasectomy, when your doctor tells you to abstain from condom-less/birthcontrol-less sex until you come back for a sperm count, take that seriously. It’s amazing how motile they are even when kinda old, and also amazing how many hang around downstream of the vas deferens after many ejaculations. And, while rare, sometimes the vas deferens do manage to reconnect. And a bonus tip along these lines: testosterone replacement, even without hCG, is not a reliable form of birth control. I’m on (and was on) TRT, without hCG, and the concentration of sperm under the scope looked higher than any YouTube video I could find at the same magnification (meanwhile my bro is taking silly amounts of hCG and struggling). I hear a lot of people joke about TRT having the beneficial side effect of infertility, but that’s far from a certainty.
  - johnisgood 1y ago
    Thank you for sharing this!
  - alabastervlog 1y ago
    Relatedly, this is also why the “failure” rate for vasectomy isn’t vanishingly close to 0%: it’s almost all dudes having unprotected sex in the first month or so after the procedure. Spontaneous reconnection happens but is extremely rare. If you can follow the doctor’s orders for a few weeks, vasectomy’s failure rate may as well be 0%.
  - harshreality 1y ago
    What's the mechanism for that? Maybe a few sperm are stuck in the sperm ducts past the point they were severed, but the ducts are cut and sealed, aren't they? Even if they weren't sealed, it would be Russian Roulette trying to get across the gap in what's effectively just body cavity space. My expectation would be the first sample might have lower but significant sperm count, and each subsequent sample would decrease dramatically until any residual sperm died and the count was zero. You're talking about motility, not count, but it doesn't sound like you noticed a drastic decrease from sample to sample. That doesn't seem right according to my understanding.
    - cstrahan 1y ago
      Well, to be clear, I didn’t actually count the sperm, as I was more interested in a rough, qualitative (rather than rigorous, quantitative) observation. That said, yeah, the relative amount of sperm didn’t drop off noticeably at the offset. And I think that kind of makes sense: as someone with a relatively short refractory period, let’s suppose I ejaculate two or three times in 5 minutes: I doubt (though I could be wrong) that my body actually evacuated all of the seminal fluid (and fully replaced it) each time. I would bet there’s simply a bunch “left in the tank”. Would be interesting to hear from a urologist (or someone with similar expertise).
- johnisgood 1y ago
  > Both mice and non-human primates fully regained fertility after stopping the drug. Mice regained fertility within six weeks, and non-human primates fully recovered their sperm count in 10-15 weeks. Hard pass on messing with my fertility like that, too, TBH.
  - slashdev 1y ago
    You realize female birth control drugs have the same lingering effect on fertility too right?
    - johnisgood 1y ago
      What exactly is your point? I have already stated my preferred methods, none of which involve hormonal birth control pills. Moreover, I have never attempted to persuade or pressure anyone into using such medications. In relationships, mutual understanding and compromise are essential. I fully acknowledge that certain decisions come with trade-offs. For example, I would not hesitate to take Silodosin and deal with its potential side effects if it benefited the relationship. I would expect the same level of consideration in return (reciprocity), but that does not equate to coercion or irresponsibility. My position remains unchanged: I would avoid hormonal contraceptives for myself, and I do not advocate their use by others. My preferred approaches are non-hormonal and do not carry such implications (as I have stated in previous comments). That said, I believe that in a committed relationship, some level of shared sacrifice or compromise is not only inevitable, but necessary. Given that, I fail to see how your point is relevant to the context of our discussion. If your intention was to imply that I expect others to make sacrifices I would not make myself, then I outright reject that assumption. Mutual responsibility, respect, and voluntary compromise are foundational to any relationship I engage in, coercion has no place in it. If this conversation is shifting from an exchange of ideas to personal insinuations, I see little value in continuing it further. Thank you. :)
      - johnisgood 1y ago
        Edit: "I would avoid hormonal contraceptives" -> "I would avoid hormonal contraceptives and pills affecting fertility in the aforementioned ways".
- herbst 1y ago
  > And that's true, anejaculatory orgasms can feel strange or less satisfying for some, but it is not universal. I would have been ok with less satisfying but it felt horrible, like it was going somewhere else instead of coming out. I wouldn't recommend this to anyone

johnisgood 1y ago

Circulatory side effects like dizziness or orthostatic hypotension do occur, though they tend to be mild and dose-dependent. You're right that it doesn't stop sperm production, just emission. As for "the drip"; that's pre-ejaculate, which doesn't contain sperm inherently, but can pick up residual sperm in the urethra from a prior ejaculation. And that's true, anejaculatory orgasms can feel strange or less satisfying for some, but it is not universal. > Otherwise if taken as a single dose fresh, side effects like orthostatic hypotension are vastly increased. That is true. Edit: I / We will have to research the side-effect profile and mechanisms of the mentioned pill (in the submission). I have not yet done so. They mention no side-effects but it might be too early to tell.

cstrahan 1y ago
> You're right that it doesn't stop sperm production, just emission. As for "the drip"; that's pre-ejaculate, which doesn't contain sperm inherently, but can pick up residual sperm in the urethra from a prior ejaculation. I’d like to stress that point a bit. I had a vasectomy about a year ago, and being the weirdo that I am, I figured I’d see how much sperm remained in my ejaculate (and for how long) after the procedure. I waited maybe two or three days after the procedure, and then for the next three days, I’d collect three samples per day and take a look under my microscope. In the first four or five samples, the swimmers were swimming hard. Told my brother (who had been trying for a kid for a couple years, and had observed his own samples trying correlate diet and other factors to improved motility) about the straight laser beams I was seeing in the scope — he nearly had a fit when I described how long it took them to go from one side of the slide to the other under the given magnification. It was the ninth sample when there were very few observable sperm, and what remained looked kinda drunk and unmotivated. All of that to say: if you’re going to get a vasectomy, when your doctor tells you to abstain from condom-less/birthcontrol-less sex until you come back for a sperm count, take that seriously. It’s amazing how motile they are even when kinda old, and also amazing how many hang around downstream of the vas deferens after many ejaculations. And, while rare, sometimes the vas deferens do manage to reconnect. And a bonus tip along these lines: testosterone replacement, even without hCG, is not a reliable form of birth control. I’m on (and was on) TRT, without hCG, and the concentration of sperm under the scope looked higher than any YouTube video I could find at the same magnification (meanwhile my bro is taking silly amounts of hCG and struggling). I hear a lot of people joke about TRT having the beneficial side effect of infertility, but that’s far from a certainty.
- johnisgood 1y ago
  Thank you for sharing this!
- alabastervlog 1y ago
  Relatedly, this is also why the “failure” rate for vasectomy isn’t vanishingly close to 0%: it’s almost all dudes having unprotected sex in the first month or so after the procedure. Spontaneous reconnection happens but is extremely rare. If you can follow the doctor’s orders for a few weeks, vasectomy’s failure rate may as well be 0%.
- harshreality 1y ago
  What's the mechanism for that? Maybe a few sperm are stuck in the sperm ducts past the point they were severed, but the ducts are cut and sealed, aren't they? Even if they weren't sealed, it would be Russian Roulette trying to get across the gap in what's effectively just body cavity space. My expectation would be the first sample might have lower but significant sperm count, and each subsequent sample would decrease dramatically until any residual sperm died and the count was zero. You're talking about motility, not count, but it doesn't sound like you noticed a drastic decrease from sample to sample. That doesn't seem right according to my understanding.
  - cstrahan 1y ago
    Well, to be clear, I didn’t actually count the sperm, as I was more interested in a rough, qualitative (rather than rigorous, quantitative) observation. That said, yeah, the relative amount of sperm didn’t drop off noticeably at the offset. And I think that kind of makes sense: as someone with a relatively short refractory period, let’s suppose I ejaculate two or three times in 5 minutes: I doubt (though I could be wrong) that my body actually evacuated all of the seminal fluid (and fully replaced it) each time. I would bet there’s simply a bunch “left in the tank”. Would be interesting to hear from a urologist (or someone with similar expertise).
johnisgood 1y ago
> Both mice and non-human primates fully regained fertility after stopping the drug. Mice regained fertility within six weeks, and non-human primates fully recovered their sperm count in 10-15 weeks. Hard pass on messing with my fertility like that, too, TBH.
- slashdev 1y ago
  You realize female birth control drugs have the same lingering effect on fertility too right?
  - johnisgood 1y ago
    What exactly is your point? I have already stated my preferred methods, none of which involve hormonal birth control pills. Moreover, I have never attempted to persuade or pressure anyone into using such medications. In relationships, mutual understanding and compromise are essential. I fully acknowledge that certain decisions come with trade-offs. For example, I would not hesitate to take Silodosin and deal with its potential side effects if it benefited the relationship. I would expect the same level of consideration in return (reciprocity), but that does not equate to coercion or irresponsibility. My position remains unchanged: I would avoid hormonal contraceptives for myself, and I do not advocate their use by others. My preferred approaches are non-hormonal and do not carry such implications (as I have stated in previous comments). That said, I believe that in a committed relationship, some level of shared sacrifice or compromise is not only inevitable, but necessary. Given that, I fail to see how your point is relevant to the context of our discussion. If your intention was to imply that I expect others to make sacrifices I would not make myself, then I outright reject that assumption. Mutual responsibility, respect, and voluntary compromise are foundational to any relationship I engage in, coercion has no place in it. If this conversation is shifting from an exchange of ideas to personal insinuations, I see little value in continuing it further. Thank you. :)
    - johnisgood 1y ago
      Edit: "I would avoid hormonal contraceptives" -> "I would avoid hormonal contraceptives and pills affecting fertility in the aforementioned ways".
herbst 1y ago
> And that's true, anejaculatory orgasms can feel strange or less satisfying for some, but it is not universal. I would have been ok with less satisfying but it felt horrible, like it was going somewhere else instead of coming out. I wouldn't recommend this to anyone