3 ms·

We don’t need a peer reviewed study to test it out. https://m.youtube.com/watch?v=Cdi0jQtMqV8&pp https://m.youtube.com/watch?v=Cdi0jQtMqV8&pp

thesparks 2y ago
Am I the only one who started to feel a bit nauseous listening to this? I'm serious.
- pomian 2y ago
  That may be a good thing. Most of the seasickness drugs make you queasy, if you don't go out on a rolling sea after taking them.
  - BugsJustFindMe 2y ago
    Uh...no... It would be completely bonkers for an antiemetic to commonly induce an emetic urge in any but rare exceptional cases. Most seasickness drugs are just first-generation antihistamines sometimes combined with a caffeine analogue to counteract the sleepiness. Dramamine/Gravol (dimenhydrinate) is just benadryl (diphenhydramine) plus the caffeine analogue theophylline. Bonine/DramamineII (meclizine) is also a first-generation antihistamine. Promethazine is also a first-generation antihistamine. Non-antihistamine antiemetics like ondansetron or scopolamine transdermal patches require a prescription from a doctor and therefore aren't commonly used for motion sickness except for occupational seafarers. And it would still be absolutely stupid if the drugs given to prevent nausea commonly caused nausea.
    - rzzzt 2y ago
      Why would it be stupid? You are concentrating on the vomiting part but aren't other sensations related to motion sickness like shaky balance that drugs could help out with?
      - OJFord 2y ago
        Not to mention the possibility of triggering a response that the trigger would help combat if you already exhibited the response. Or it simply being an uncommon side effect that it's made worse. Headaches and nausea are listed in possible side effects for just about everything, because if anyone reports it they have to list it since the possibility of causality hasn't been ruled out.
        dcow 2y ago
        Does that mean when death is listed that somebody died during the trial?
      - BugsJustFindMe 2y ago
        > You are concentrating on the vomiting part The nausea part. The person I'm replying to specifically said "queasy".
    - DrBenCarson 2y ago
      I think it’s not uncommon for a drug treating some condition with some symptom to have a potential side effect that worsens that symptom. When you start playing with some set of receptors, it’s possible something goes too far or, for whatever reason, not far enough and now we’re worse off See: antidepressants can increase suicidal ideation, cannabis (used for nausea) can cause nausea at higher doses, etc.
      - xico 2y ago
        As an occasional user, can confirm that motion sickness pills (e.g. Cinnarizine, one of the most used in the British Navy) make dizzy, some more than other, and that it’s still much better overall than not taking them.
      - BugsJustFindMe 2y ago
        > I think it’s not uncommon for a drug treating some condition with some symptom to have a potential side effect that worsens that symptom. I think you're making the error of conflating probabilities here. It's not uncommon for drugs to have uncommon side effects, but those side effects are still uncommon. Every once in a while benadryl makes a person paradoxically excited, but most people who take benadryl get sleepy.
- Angostura 2y ago
  it made me feel slightly uneasy. Brains are weird
pipes 2y ago
Should I have been able to hear something? I feel like my ears need popped now
- tgv 2y ago
  It's a sine (or sine-like) sound at a low pitch (around G2). Our ears aren't great at those frequencies, and the speaker you use might be bad at that range too. It's a bass frequency, but most bass sounds have a lot of overtones, which makes them sound clearer than the fundamental.
  - pipes 2y ago
    Thanks
marci 2y ago
and to test it here (it might be very loud!): CTRL+SHIFT+I and in the console let o, a=new AudioContext(); document.addEventListener("mousedown",function(){ if (o) {o.stop(); o = undefined} else{ o=a.createOscillator(); o.type="sine"; o.frequency.value=100; o.connect(a.destination);o.start()} }) If you click anywhere it will start/stop.
- skykooler 2y ago
  It sounds like a pitch that you might hear from an airplane propeller, which leads to the question why airsickness exists if the antidote is ambiently present?

thesparks 2y ago

Am I the only one who started to feel a bit nauseous listening to this? I'm serious.

pomian 2y ago
That may be a good thing. Most of the seasickness drugs make you queasy, if you don't go out on a rolling sea after taking them.
- BugsJustFindMe 2y ago
  Uh...no... It would be completely bonkers for an antiemetic to commonly induce an emetic urge in any but rare exceptional cases. Most seasickness drugs are just first-generation antihistamines sometimes combined with a caffeine analogue to counteract the sleepiness. Dramamine/Gravol (dimenhydrinate) is just benadryl (diphenhydramine) plus the caffeine analogue theophylline. Bonine/DramamineII (meclizine) is also a first-generation antihistamine. Promethazine is also a first-generation antihistamine. Non-antihistamine antiemetics like ondansetron or scopolamine transdermal patches require a prescription from a doctor and therefore aren't commonly used for motion sickness except for occupational seafarers. And it would still be absolutely stupid if the drugs given to prevent nausea commonly caused nausea.
  - rzzzt 2y ago
    Why would it be stupid? You are concentrating on the vomiting part but aren't other sensations related to motion sickness like shaky balance that drugs could help out with?
    - OJFord 2y ago
      Not to mention the possibility of triggering a response that the trigger would help combat if you already exhibited the response. Or it simply being an uncommon side effect that it's made worse. Headaches and nausea are listed in possible side effects for just about everything, because if anyone reports it they have to list it since the possibility of causality hasn't been ruled out.
      - dcow 2y ago
        Does that mean when death is listed that somebody died during the trial?
    - BugsJustFindMe 2y ago
      > You are concentrating on the vomiting part The nausea part. The person I'm replying to specifically said "queasy".
  - DrBenCarson 2y ago
    I think it’s not uncommon for a drug treating some condition with some symptom to have a potential side effect that worsens that symptom. When you start playing with some set of receptors, it’s possible something goes too far or, for whatever reason, not far enough and now we’re worse off See: antidepressants can increase suicidal ideation, cannabis (used for nausea) can cause nausea at higher doses, etc.
    - xico 2y ago
      As an occasional user, can confirm that motion sickness pills (e.g. Cinnarizine, one of the most used in the British Navy) make dizzy, some more than other, and that it’s still much better overall than not taking them.
    - BugsJustFindMe 2y ago
      > I think it’s not uncommon for a drug treating some condition with some symptom to have a potential side effect that worsens that symptom. I think you're making the error of conflating probabilities here. It's not uncommon for drugs to have uncommon side effects, but those side effects are still uncommon. Every once in a while benadryl makes a person paradoxically excited, but most people who take benadryl get sleepy.
Angostura 2y ago
it made me feel slightly uneasy. Brains are weird

pipes 2y ago

Should I have been able to hear something? I feel like my ears need popped now

tgv 2y ago
It's a sine (or sine-like) sound at a low pitch (around G2). Our ears aren't great at those frequencies, and the speaker you use might be bad at that range too. It's a bass frequency, but most bass sounds have a lot of overtones, which makes them sound clearer than the fundamental.
- pipes 2y ago
  Thanks

marci 2y ago

and to test it here (it might be very loud!): CTRL+SHIFT+I and in the console let o, a=new AudioContext(); document.addEventListener("mousedown",function(){ if (o) {o.stop(); o = undefined} else{ o=a.createOscillator(); o.type="sine"; o.frequency.value=100; o.connect(a.destination);o.start()} }) If you click anywhere it will start/stop.

skykooler 2y ago
It sounds like a pitch that you might hear from an airplane propeller, which leads to the question why airsickness exists if the antidote is ambiently present?