4 ms·
I too think that we don't yet have convincing evidence that recent changes in global temperature have driven thermal tolerance. However, there are some interest
by pmags 1y ago
I too think that we don't yet have convincing evidence that recent changes in global temperature have driven thermal tolerance. However, there are some interesting aspect of C. auris that are worth pointing out:
• C. auris does have unusual thermotolerance -- it grows up to 42C which is unusual compared to other Candida species.
• C. auris does not appear to be a typical commensal of mammals, or other high body temp animals, and hence it's thermal tolerance is likely not due to selection for this aspect of the host niche
Some more info on C. auris and hypotheses about origins here:
• Sharma C, Kadosh D. Perspective on the origin, resistance, and spread of the emerging human fungal pathogen Candida auris. PLoS Pathog. 2023 Mar 23;19(3):e1011190. doi: 10.1371/journal.ppat.1011190. PMID: 36952448; PMCID: PMC10035752.
But I agree