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Show HN: AIDO.ModelGenerator and Expanded Foundation Model Suite
GenBio AI just released an update to AIDO.ModelGenerator, a software package for adapting, benchmarking, and applying biological foundation models across multiple tasks and data types.
What it is
AIDO.ModelGenerator supports both GenBio AI models and popular open-source models like Enformer, ESM2, and scFoundation. It enables workflows for structure prediction, protein modeling, single-cell analysis, and spatial transcriptomics.
What’s new
New models:
• AIDO.StructurePrediction – biomolecular structure prediction across proteins, RNA, DNA, and ligands
• AIDO.Protein-RAG – protein modeling with MSA and structure input
• AIDO.Tissue – spatially aware cell modeling
New benchmark datasets:
• Cell age prediction
• Cell-type classification
• Cellular perturbation (Tahoe-100M)
Utilities for distributed training and hyperparameter tuning
Use cases Includes tutorials for:
• mRNA vaccine design
• Predicting protein complexes
• Simulated gene knockouts for target discovery