Ejecting/flushing them out periodically, and starting over, as it is done for many other agroindustrially used cell cultures already? Cheese comes to mind, Qor

Ejecting/flushing them out periodically, and starting over, as it is done for many other agroindustrially used cell cultures already? Cheese comes to mind, Qorn, aromes in cell cultures on wet sawdust sold as 'nature identical', countless more I don't remember ATM.