At least on Mac, when you install them locally, Creative Cloud makes them available to every app like any other font. They’re just regular OpenType files, albe

At least on Mac, when you install them locally, Creative Cloud makes them available to every app like any other font. They’re just regular OpenType files, albeit with “beware of the leopard” levels of filesystem obfuscation, so it’s fairly trivial to divorce them from Creative Cloud’s control if you want/need to. And on the web, Typekit is just CSS and woff(2), so again, no (technical) impediment to doing whatever you want with them.