Unfortunately, in terms of antifungals both the EU and US are still using tons of them in the context of agriculture [1] which is contributing to drug resistanc

Unfortunately, in terms of antifungals both the EU and US are still using tons of them in the context of agriculture [1] which is contributing to drug resistance of human pathogenic fungi [2]. The references below focus on Aspergillus, but there are many such example in other fungal pathogens. [1] Impact of the use of azole fungicides, other than as human medicines, on the development of azole‐resistant Aspergillus spp. https://www.efsa.europa.eu/en/efsajournal/pub/9200 https://www.efsa.europa.eu/en/efsajournal/pub/9200 [2] Celia-Sanchez BN, Mangum B, Gómez Londoño LF, Wang C, Shuman B, Brewer MT, Momany M. Pan-azole- and multi-fungicide-resistant Aspergillus fumigatus is widespread in the United States. Appl Environ Microbiol. 2024 Apr 17;90(4):e0178223. doi: 10.1128/aem.01782-23. Epub 2024 Apr 1. PMID: 38557086; PMCID: PMC11022549.