In addition to electronic singalling being completely different, the serial interface used by many 3d printers is not the same as low level serial interface sen

In addition to electronic singalling being completely different, the serial interface used by many 3d printers is not the same as low level serial interface sent over the wire. There is a low level usb protocol for stuff like data packets ,checksums , metadata negotiation, multiple endpoints in single device, basic transfer types(bulk, isochronous, control, interrupt). All common device types and standard drivers including USB to serial, HID, removable storage is built on top of this layer instead of raw serial sent over the wire. That's why you can have stuff like USB hubs which can forward data to and from multiple devices. And also why you can plug in a USB device, and the OS recognize and lookup driver without user manually configuring what device is plugged into which port.