It depends on the hardware. The laptop I use for DJ doesn't have a dedicated GPU. I also use open source, preferring demucs over spleeter. In my experience sp

It depends on the hardware. The laptop I use for DJ doesn't have a dedicated GPU. I also use open source, preferring demucs over spleeter. In my experience spleeter requires huge amounts of memory, my DJ laptop only has 16GB of RAM, and I need to close the browser to be able to successfully stem a 5 minutes song. Demucs takes a bit longer, but it uses just 2GB of RAM. And the sound quality of the stems separation is much better with demucs, which is a more important factor than the runtime, IMO.