4 ms·
the bodybuilding scene has gotten more advanced than just steriods, for example: - SARMs (selective androgen receptor modulators) - eg ostarine - they hit you
by amy_petrik 2y ago
the bodybuilding scene has gotten more advanced than just steriods, for example:
- SARMs (selective androgen receptor modulators) - eg ostarine - they hit your muscles androgen receptors selectively, nominally other receptors (ie reproductive) are skipped over
- SERMS (selective estrogen receptor modulators) - typically used to reduce gynecomastia after steroid use, but interestingly one, clomiphene or enclomiphene, blocks estrogen reception in the pituitary, making it think hormone production is too low - so tells your body to manufacture more testosterone (yes, estrogen receptor blockage yields testosterone production).. this is the closest we have to a fertility drug and is prescribed as a fertility drug in women
- cardarine - PPAR delta activator, activates metabolic pathways and used by athletes for doping - quite an interesting drug because it normalizes one's metabolism, increases athletic performance, lowers cholesterol, etc, wow! though to activate a particular minor cancer pathway.. never tested in humans since it gave animal models turbocancer. used by many athletes
But yea, most of these are going to blanket increase risks for various things - strokes, clot, heart attack... messing about with hormones can be quite damaging albeit I would take a SARM or a SERM before taking straight hormones. Cardarine is quite scary because of the cancer concern
- loeg 2y agoSARMs are just relatively ineffective anabolic steroids. They likely have the same health drawbacks, through the same mechanisms, in addition to the drawbacks of being understudied and less effective. SERMs aren't muscle-building. Don't take SARMs or other AAS (aside from TRT under the supervision of a physician) unless you want to die young.