Yes, Citicoline is great, too, I agree. As long as it is not Choline bitartrate (most common form) which is pretty useless, the body cannot utilize it whatsoeve

Yes, Citicoline is great, too, I agree. As long as it is not Choline bitartrate (most common form) which is pretty useless, the body cannot utilize it whatsoever. As for what you said regarding alpha-GPC, it is somewhat true: > Although alpha-GPC is largely considered to be safe due to its structural feature, multiple studies have indicated that a high plasma choline level is associated with an increased risk of cardiovascular disease through trimethylamine-N-oxide (TMAO) produced by gut microbiota from choline. Some studies have highlighted that TMAO increases the likelihood of stroke and cardiovascular disease.11 > In line with this observation, a recent animal model study revealed that even though alpha-GPC supplements improved neurological functions, they increased the risk of atherosclerosis in hyperlipidemic rats. In the future, scientists must elucidate the possible mechanism that associates alpha-GPC with increased cardiovascular risks. https://examine.com/supplements/alpha-gpc/?show_conditions=true https://examine.com/supplements/alpha-gpc/?show_conditions=t... https://www.news-medical.net/health/Alpha-GPC-What-Science-Says-About-Its-Role-in-Brain-Health.aspx https://www.news-medical.net/health/Alpha-GPC-What-Science-S... https://pmc.ncbi.nlm.nih.gov/articles/PMC8708068/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8708068/ https://www.sciencedirect.com/science/article/pii/S0021925824024670 https://www.sciencedirect.com/science/article/pii/S002192582... That said, "However, the currently available evidence is preliminary in nature, so randomized controlled trials and large cohort studies are needed to confirm these findings.".