3 ms·
Sadly that reminds me how positive covid antibody test results haven't been a valid immunization attestation. Maybe this type of bispecific antibodies could be
by sharpshadow 2y ago
Sadly that reminds me how positive covid antibody test results haven't been a valid immunization attestation.
Maybe this type of bispecific antibodies could be used to neutralize the spike protein which the body produces through the vaccine. As far as I understand the targeted deltoid muscle is a cell with a long life therefore procuding and releasing spikes for a yet unkown timeframe. Given the various specific boosters I can imagine one taking neutralizing antibodies to avoid a constant immune system stimulation.
- z991 2y agoThere's an important detail here -- an advantage of mRNA vaccines is that mRNA does not last all that long in cells [1]. Thus, even if the cells live a long time, they won't produce spike proteins for very long (instructions for the production will be degraded and thus not available). The vaccine's longer-term effectiveness comes from the immune system's memory B cells response to the short-lived expression of spike proteins. [1] https://en.m.wikipedia.org/wiki/Messenger_RNA#Degradation https://en.m.wikipedia.org/wiki/Messenger_RNA#Degradation
- weaksauce 2y agoyou mean memory T cell right? As I understand it B cells are created by T cells to an acute infection.(they also kill infected cells but this is a gross simplification and i'm not a epidemiologist.)
- jbritton 2y agoSome individuals have spike protein after 700 days. https://news.yale.edu/2025/02/19/immune-markers-post-vaccination-syndrome-indicate-future-research-directions https://news.yale.edu/2025/02/19/immune-markers-post-vaccina...