Note that 210 mcg/L is 210 ng/milliliter. The molecular weight of norharman is 168.2 g/mol, so the concentration is about 1250 nM/L. Coupled with frequency of

Note that 210 mcg/L is 210 ng/milliliter. The molecular weight of norharman is 168.2 g/mol, so the concentration is about 1250 nM/L. Coupled with frequency of coffee intake and accounting for storage in adipose tissue, levels in vivo could easily exceed binding affinities after just days or weeks of coffee use.