7 ms·

Can’t comment on the technical quality of this paper but wanted to highlight that the research was funded by the NIH which our government is currently chaotical

Can’t comment on the technical quality of this paper but wanted to highlight that the research was funded by the NIH which our government is currently chaotically gutting. Link to paper: https://www.nature.com/articles/s41467-025-56461-1.pdf https://www.nature.com/articles/s41467-025-56461-1.pdf

AnthonBerg 2y ago
Thank you!
dpatru 2y ago
[flagged]
- 0x70dd 2y ago
  You should take everything he says with a grain of salt. He’s defunding research on transgenic mice, not transgender.
  - gryfft 2y ago
    [flagged]
    - javiramos 2y ago
      /s?
  - bhk 2y ago
    Where did this bogus "transgenic" narrative come from? And BTW he didn't say "research on transgender mice", he said "making mice transgender"... which is technically incorrect but obvious to me (and, I thought, anyone knowledgeable in the field) that the research involved giving mice hormone therapy. https://www.cnn.com/2025/03/04/politics/fact-check-trump-address-congress/index.html https://www.cnn.com/2025/03/04/politics/fact-check-trump-add...
    - simtel20 2y ago
      Saying "technically incorrect" is downplaying what is really totally incorrect from any reasonable interpretation. There is nothing in that fact check that it's close to what was said. Let's just call it wrong and not try to excuse it
    - daveguy 2y ago
      The ability to turn a study on "the effects of testosterone hormone therapy on breast cancer" into "transgender", into "why are they twisting his words! everyone knows he didn't mean transgender" requires some serious excuse making mental gymnastics. Why are you still trying to convince yourself rather than just recognize maga has gone completely off the rails?
      - bhk 2y ago
        Where did "transgenic" come from?
- op00to 2y ago
  Please refrain from posting deliberately misleading and inflammatory statements here. The studies in question involve administering hormonal treatments to mice to investigate health outcomes relevant to humans, not altering the gender identity of mice. https://www.rollingstone.com/politics/politics-news/trump-transgender-mice-medical-research-1235289439/ https://www.rollingstone.com/politics/politics-news/trump-tr...
  - yimby2001 2y ago
    Interesting times indeed https://www.whitehouse.gov/articles/2025/03/yes-biden-spent-millions-on-transgender-animal-experiments/ https://www.whitehouse.gov/articles/2025/03/yes-biden-spent-...
    - sennalen 2y ago
      They are not "transgender mice studies". They are human health studies using mice as a model animal, as is routine in biological research.
      - yimby2001 2y ago
        $455,000: “A Mouse Model to Test the Effects of Gender-affirming Hormone Therapy on HIV Vaccine-induced Immune Responses
        throaway1989 2y ago
        but they are not searching for a way to make mice transgender. The point of the research is to model those effects as they might occur in humans, not to figure out how to make transgender mice.
        genewitch 2y ago
        Which effects? Why should a taxpayer care?
- whileromeburns 2y ago
  It was good research, Duke was doing a study on optimizing the HIV vaccine in a high risk group—work that benefits us all: https://reason.com/2025/03/06/no-hhs-didnt-spend-8-million-making-mice-transgender/ https://reason.com/2025/03/06/no-hhs-didnt-spend-8-million-m...
- andrewl 2y ago
  The gen part of transgenic comes from genes, not gender. Transgenic refers to an organism or cell whose genome has been altered by the introduction of one or more foreign DNA sequences from another species by artificial means.[1][2] Trumps’s team grabbed the term to anger credulous people and get their support. Trump might not know what it means, but his team does, and they don’t care. I expect depatru knows what it means as well, or is capable of finding it out. But he’d rather add to the manipulation. I’m linking to both genome.gov and to Wikipedia in case the government site is taken down. [1]https://www.genome.gov/genetics-glossary/Transgenic https://www.genome.gov/genetics-glossary/Transgenic [2]https://en.wikipedia.org/wiki/Transgene https://en.wikipedia.org/wiki/Transgene
  - zoklet-enjoyer 2y ago
    Animal testing should be banned, so that's fine
    - dangerlibrary 2y ago
      The shadow druids are gaining a foothold in Silicon Valley circles, it seems.
      - Henchman21 2y ago
        Idiocy is gaining a foothold everywhere it seems to me. I keep wondering if this is how civilization collapses? We just forget how to do stuff and recede back into darkness?
    - ricardonunez 2y ago
      Then ban animal testing no stopping the whole research funding but that’s not the reason why the funding stopped.
- dpatru 2y ago
  The posted article was about research to cure blindness with stem cells. The top comment implied that such research was being defunded. I asked for an example that was not about defunding research on transgender mice. The only examples provided were for research that was confused with transgender research. So it seems that Doge is not cutting research for curing blindness and the like but only for transgender and some related-sounding other studies that were lumped in together, which will probably be sorted out in time.
  - tomrod 2y ago
    I believe you may be making your conclusion too early.
  - Buttons840 2y ago
    They seem to be making broad cuts that will effect all research: https://apnews.com/article/trump-cuts-research-funding-nih-duke-7f24b33bbad54490583520536ab40e0c https://apnews.com/article/trump-cuts-research-funding-nih-d...
    - dpatru 2y ago
      Your article says that Duke University is shutting down research because the government is cutting overhead allocation from 61% to 15%.
- brookst 2y ago
  The president embarrassed himself by mistaking “transgenic” for “transgender”, and a good segment of the population further embarrassed themselves by embracing confirmation bias rather than stopping to think “wait, what can’t be right”.

AnthonBerg 2y ago

Thank you!

dpatru 2y ago

[flagged]

0x70dd 2y ago
You should take everything he says with a grain of salt. He’s defunding research on transgenic mice, not transgender.
- gryfft 2y ago
  [flagged]
  - javiramos 2y ago
    /s?
- bhk 2y ago
  Where did this bogus "transgenic" narrative come from? And BTW he didn't say "research on transgender mice", he said "making mice transgender"... which is technically incorrect but obvious to me (and, I thought, anyone knowledgeable in the field) that the research involved giving mice hormone therapy. https://www.cnn.com/2025/03/04/politics/fact-check-trump-address-congress/index.html https://www.cnn.com/2025/03/04/politics/fact-check-trump-add...
  - simtel20 2y ago
    Saying "technically incorrect" is downplaying what is really totally incorrect from any reasonable interpretation. There is nothing in that fact check that it's close to what was said. Let's just call it wrong and not try to excuse it
  - daveguy 2y ago
    The ability to turn a study on "the effects of testosterone hormone therapy on breast cancer" into "transgender", into "why are they twisting his words! everyone knows he didn't mean transgender" requires some serious excuse making mental gymnastics. Why are you still trying to convince yourself rather than just recognize maga has gone completely off the rails?
    - bhk 2y ago
      Where did "transgenic" come from?
op00to 2y ago
Please refrain from posting deliberately misleading and inflammatory statements here. The studies in question involve administering hormonal treatments to mice to investigate health outcomes relevant to humans, not altering the gender identity of mice. https://www.rollingstone.com/politics/politics-news/trump-transgender-mice-medical-research-1235289439/ https://www.rollingstone.com/politics/politics-news/trump-tr...
- yimby2001 2y ago
  Interesting times indeed https://www.whitehouse.gov/articles/2025/03/yes-biden-spent-millions-on-transgender-animal-experiments/ https://www.whitehouse.gov/articles/2025/03/yes-biden-spent-...
  - sennalen 2y ago
    They are not "transgender mice studies". They are human health studies using mice as a model animal, as is routine in biological research.
    - yimby2001 2y ago
      $455,000: “A Mouse Model to Test the Effects of Gender-affirming Hormone Therapy on HIV Vaccine-induced Immune Responses
      - throaway1989 2y ago
        but they are not searching for a way to make mice transgender. The point of the research is to model those effects as they might occur in humans, not to figure out how to make transgender mice.
        genewitch 2y ago
        Which effects? Why should a taxpayer care?
whileromeburns 2y ago
It was good research, Duke was doing a study on optimizing the HIV vaccine in a high risk group—work that benefits us all: https://reason.com/2025/03/06/no-hhs-didnt-spend-8-million-making-mice-transgender/ https://reason.com/2025/03/06/no-hhs-didnt-spend-8-million-m...
andrewl 2y ago
The gen part of transgenic comes from genes, not gender. Transgenic refers to an organism or cell whose genome has been altered by the introduction of one or more foreign DNA sequences from another species by artificial means.[1][2] Trumps’s team grabbed the term to anger credulous people and get their support. Trump might not know what it means, but his team does, and they don’t care. I expect depatru knows what it means as well, or is capable of finding it out. But he’d rather add to the manipulation. I’m linking to both genome.gov and to Wikipedia in case the government site is taken down. [1]https://www.genome.gov/genetics-glossary/Transgenic https://www.genome.gov/genetics-glossary/Transgenic [2]https://en.wikipedia.org/wiki/Transgene https://en.wikipedia.org/wiki/Transgene
- zoklet-enjoyer 2y ago
  Animal testing should be banned, so that's fine
  - dangerlibrary 2y ago
    The shadow druids are gaining a foothold in Silicon Valley circles, it seems.
    - Henchman21 2y ago
      Idiocy is gaining a foothold everywhere it seems to me. I keep wondering if this is how civilization collapses? We just forget how to do stuff and recede back into darkness?
  - ricardonunez 2y ago
    Then ban animal testing no stopping the whole research funding but that’s not the reason why the funding stopped.
dpatru 2y ago
The posted article was about research to cure blindness with stem cells. The top comment implied that such research was being defunded. I asked for an example that was not about defunding research on transgender mice. The only examples provided were for research that was confused with transgender research. So it seems that Doge is not cutting research for curing blindness and the like but only for transgender and some related-sounding other studies that were lumped in together, which will probably be sorted out in time.
- tomrod 2y ago
  I believe you may be making your conclusion too early.
- Buttons840 2y ago
  They seem to be making broad cuts that will effect all research: https://apnews.com/article/trump-cuts-research-funding-nih-duke-7f24b33bbad54490583520536ab40e0c https://apnews.com/article/trump-cuts-research-funding-nih-d...
  - dpatru 2y ago
    Your article says that Duke University is shutting down research because the government is cutting overhead allocation from 61% to 15%.
brookst 2y ago
The president embarrassed himself by mistaking “transgenic” for “transgender”, and a good segment of the population further embarrassed themselves by embracing confirmation bias rather than stopping to think “wait, what can’t be right”.