4 ms·

I know guys who have taken testosterone enanthate to get bigger, and the side effects have been CRAZY! To be fair, the increase in strength, stamina and restitu

I know guys who have taken testosterone enanthate to get bigger, and the side effects have been CRAZY! To be fair, the increase in strength, stamina and restitution equally so.. I know it’s very dose dependent, but typical steroid doses are 10-100x what your body produces naturally(!). I don’t know how it compares to “clinical doses”, but think twice man…

Aurornis 2y ago
For men who are truly deficient (not the podcaster/TRT clinic definition where everyone is deficient) going on a true replacement dose of TRT is a good life improvement. Even those patients are often disappointed when the TRT doesn’t solve their problems. The high doses used by TRT clinics shoot past that threshold and go for levels that were previously only used by people using testosterone for performance enhancement. The really hard thing about this topic is that a lot of the negative effects don’t show up right away. It’s sometimes months or years later before people realize their testes are so shut down that they’re dependent on TRT for life, for example. People also go into loops of trying to manage high estrogen (a side effect of high TRT doses) where they crash their estrogen, going into deep depression, or get it wrong and end up growing excessive breast tissue that needs to be physically removed. High testosterone levels (beyond normal physiological range) are also associated with lower cognition. It makes people feel more confident, though, so this also isn’t noticed. Anxiety disorders are also a common side effect of excessive dosing. The list goes on and on. Unfortunately mainstream podcasts on this topic are woefully bad at covering it because they know listeners only want to hear about the positives. Even the supposedly good podcasts like Huberman Lab are a joke on this topic. The TRT forum people love picking apart how bad Huberman’s TRT takes are, even though he positions himself as being moderate on the subject.
arwhatever 2y ago
Might not be HN-worthy conversation, but I often reflect on how funny this piece of satire is: https://clickhole.com/i-know-this-sounds-like-spam-but-i-really-did-double-m-1825123933/ https://clickhole.com/i-know-this-sounds-like-spam-but-i-rea...
spondylosaurus 2y ago
Funny story about testosterone enanthate dosing... so, I take it for body image/dysphoria reasons (to make myself more androgynous, basically) but I'm not a cisgender man. My body produces very little testosterone on its own. The doctor started me on a "midrange" dose of enanthate: 75mg every 10 days. My levels shot up, at the very high end of the male range. I brought that down to 75mg every 2 weeks and it barely budged. This is the exact same drug/formulation that a lot of these guys are taking for TRT. The highest "official" dose is 100mg every 7 days. (I'm sure some of them are taking even more than that, but that's as much as a doctor should be prescribing you.) Obviously everyone metabolizes this stuff differently, and if you're tall/heavy you'll likely need a higher dose than someone of average stature like me. But if my T levels shot up from ~20 ng/dL* to ~900 on a very moderate dose of enanthate, how high are those levels getting for someone who's starting from ~500? * The normal female range is anywhere from 15 to 70. The normal male range is anywhere from 200 to 1000.

Aurornis 2y ago

For men who are truly deficient (not the podcaster/TRT clinic definition where everyone is deficient) going on a true replacement dose of TRT is a good life improvement. Even those patients are often disappointed when the TRT doesn’t solve their problems. The high doses used by TRT clinics shoot past that threshold and go for levels that were previously only used by people using testosterone for performance enhancement. The really hard thing about this topic is that a lot of the negative effects don’t show up right away. It’s sometimes months or years later before people realize their testes are so shut down that they’re dependent on TRT for life, for example. People also go into loops of trying to manage high estrogen (a side effect of high TRT doses) where they crash their estrogen, going into deep depression, or get it wrong and end up growing excessive breast tissue that needs to be physically removed. High testosterone levels (beyond normal physiological range) are also associated with lower cognition. It makes people feel more confident, though, so this also isn’t noticed. Anxiety disorders are also a common side effect of excessive dosing. The list goes on and on. Unfortunately mainstream podcasts on this topic are woefully bad at covering it because they know listeners only want to hear about the positives. Even the supposedly good podcasts like Huberman Lab are a joke on this topic. The TRT forum people love picking apart how bad Huberman’s TRT takes are, even though he positions himself as being moderate on the subject.

arwhatever 2y ago

Might not be HN-worthy conversation, but I often reflect on how funny this piece of satire is: https://clickhole.com/i-know-this-sounds-like-spam-but-i-really-did-double-m-1825123933/ https://clickhole.com/i-know-this-sounds-like-spam-but-i-rea...

spondylosaurus 2y ago

Funny story about testosterone enanthate dosing... so, I take it for body image/dysphoria reasons (to make myself more androgynous, basically) but I'm not a cisgender man. My body produces very little testosterone on its own. The doctor started me on a "midrange" dose of enanthate: 75mg every 10 days. My levels shot up, at the very high end of the male range. I brought that down to 75mg every 2 weeks and it barely budged. This is the exact same drug/formulation that a lot of these guys are taking for TRT. The highest "official" dose is 100mg every 7 days. (I'm sure some of them are taking even more than that, but that's as much as a doctor should be prescribing you.) Obviously everyone metabolizes this stuff differently, and if you're tall/heavy you'll likely need a higher dose than someone of average stature like me. But if my T levels shot up from ~20 ng/dL* to ~900 on a very moderate dose of enanthate, how high are those levels getting for someone who's starting from ~500? * The normal female range is anywhere from 15 to 70. The normal male range is anywhere from 200 to 1000.