If you were physically active enough and careful about your diet you likely wouldn't be on a GPL-1 drug. That's the point. People end up in bad shape for a lot

If you were physically active enough and careful about your diet you likely wouldn't be on a GPL-1 drug. That's the point. People end up in bad shape for a lot of reasons, including injury. The search for a mechanism to burn fat without losing muscle is to help support people who are on GLP-1 drug because for whatever reason they were insufficiently active.