3 ms·

I’m not sure that’s exactly what’s happening with GLP-1 drugs. I lost 40 pounds very quickly on them and hurt my hip then my shoulder then my wrist. Felt like I

by wincy 2y ago

I’m not sure that’s exactly what’s happening with GLP-1 drugs. I lost 40 pounds very quickly on them and hurt my hip then my shoulder then my wrist. Felt like I was constantly getting muscle strains and random injuries. I started drinking a protein shake once a day and the random mysterious injuries stopped.

lores 2y ago
I'm on them too, and after being seriously grumpy for a while it dawned on me that not being hungry doesn't mean my body doesn't need satisfying food. I think it's easy to fall into 'don't need to eat, won't eat' and then get some form of malnutrition. I force myself to make good food and just eat less of it, so far it worked *fingers crossed*
droopyEyelids 2y ago
What you described doesn’t seem to be in conflict with what he described
- wincy 2y ago
  If the muscles had been reducing in concert with the reduced musculature needs of my body I wouldn’t be injuring myself.
aaronblohowiak 2y ago
the caloric restriction that these drugs engender can indeed lead to various forms of under-nourishment. as you point out, your protein needs (as a proportion of calorie sources) go UP when you are in caloric restriction; see PSMF.
olalonde 2y ago
A single protein shake typically provides around 22g of protein, which is a small portion of the recommended daily intake for maintaining muscle, generally close to 1g of protein per pound of body weight. As an example, I'm currently on a weight loss diet and have a 180g of proteins target per day. Unless you were significantly under-consuming protein, it's unlikely that the shake alone made a major difference.
- im3w1l 2y ago
  Such high recommendations are for people that want to maximize muscle retention / growth not people that just want to be healthy. You can get by on much less.
  - olalonde 2y ago
    Right but even on the low end of recommended daily protein intake, 22g would probably still be a small fraction.
    - im3w1l 2y ago
      The RDA is 0.37 g/pound. For a 180 pound guy, that means 67g of protein. That might sound low, but wait... At least according to this one page I found, 25% of American adults eat below RDA. It's not hard to imagine then that there are many people for whom 22g extra could make a decent difference.
      - olalonde 2y ago
        0.37g/pound is on the very very low end though, far from optimal on a weight loss diet. See this article: https://www.healthline.com/nutrition/high-protein-diet-plan#daily-protein-requirements https://www.healthline.com/nutrition/high-protein-diet-plan#... > The Recommended Dietary Allowance (RDA) of protein is 0.8 g per kilogram of body weight (g/kg/bw), or 0.36 g per pound of body weight (g/lbs/bw). > However, the authors of a 2019 review suggest that this number is often misinterpreted as the ideal number. It’s only the minimum amount of protein required to prevent nutrient deficiencies and muscle loss in most healthy individuals. > A 2017 study found that participants who ate a high protein diet of 1.34 g/kg/bw (0.6 g/lbs/bw) for more than 75% of the 6-month duration experienced significantly more weight loss than the group who followed the RDA requirements. > A 2016 review found that eating up to 2 g/kg/bw (0.9 g/lbs/bw) may help promote strength and prevent muscle degeneration. etc.
        im3w1l 2y ago
cthalupa 2y ago
This is likely just from losing weight rapidly in general. We see it with people losing weight from a variety of other sources, too. It's possible GLP-1s might enhance the effect in some way, but it's already a significant enough issue in general that adequate protein intake + some resistance training is important regardless.

by wincy 2y ago

lores 2y ago

I'm on them too, and after being seriously grumpy for a while it dawned on me that not being hungry doesn't mean my body doesn't need satisfying food. I think it's easy to fall into 'don't need to eat, won't eat' and then get some form of malnutrition. I force myself to make good food and just eat less of it, so far it worked *fingers crossed*

droopyEyelids 2y ago

What you described doesn’t seem to be in conflict with what he described

wincy 2y ago
If the muscles had been reducing in concert with the reduced musculature needs of my body I wouldn’t be injuring myself.

aaronblohowiak 2y ago

the caloric restriction that these drugs engender can indeed lead to various forms of under-nourishment. as you point out, your protein needs (as a proportion of calorie sources) go UP when you are in caloric restriction; see PSMF.

olalonde 2y ago

A single protein shake typically provides around 22g of protein, which is a small portion of the recommended daily intake for maintaining muscle, generally close to 1g of protein per pound of body weight. As an example, I'm currently on a weight loss diet and have a 180g of proteins target per day. Unless you were significantly under-consuming protein, it's unlikely that the shake alone made a major difference.

im3w1l 2y ago
Such high recommendations are for people that want to maximize muscle retention / growth not people that just want to be healthy. You can get by on much less.
- olalonde 2y ago
  Right but even on the low end of recommended daily protein intake, 22g would probably still be a small fraction.
  - im3w1l 2y ago
    The RDA is 0.37 g/pound. For a 180 pound guy, that means 67g of protein. That might sound low, but wait... At least according to this one page I found, 25% of American adults eat below RDA. It's not hard to imagine then that there are many people for whom 22g extra could make a decent difference.
    - olalonde 2y ago
      0.37g/pound is on the very very low end though, far from optimal on a weight loss diet. See this article: https://www.healthline.com/nutrition/high-protein-diet-plan#daily-protein-requirements https://www.healthline.com/nutrition/high-protein-diet-plan#... > The Recommended Dietary Allowance (RDA) of protein is 0.8 g per kilogram of body weight (g/kg/bw), or 0.36 g per pound of body weight (g/lbs/bw). > However, the authors of a 2019 review suggest that this number is often misinterpreted as the ideal number. It’s only the minimum amount of protein required to prevent nutrient deficiencies and muscle loss in most healthy individuals. > A 2017 study found that participants who ate a high protein diet of 1.34 g/kg/bw (0.6 g/lbs/bw) for more than 75% of the 6-month duration experienced significantly more weight loss than the group who followed the RDA requirements. > A 2016 review found that eating up to 2 g/kg/bw (0.9 g/lbs/bw) may help promote strength and prevent muscle degeneration. etc.
      - im3w1l 2y ago

cthalupa 2y ago

This is likely just from losing weight rapidly in general. We see it with people losing weight from a variety of other sources, too. It's possible GLP-1s might enhance the effect in some way, but it's already a significant enough issue in general that adequate protein intake + some resistance training is important regardless.