4 ms·
As much as i like the idea--but this project will not prevent any fraud. It begins with what you load into the PCR thermocycler. Samples, controls, primers are
by enopod_ 2y ago
As much as i like the idea--but this project will not prevent any fraud. It begins with what you load into the PCR thermocycler. Samples, controls, primers are all things that can easily be manipulated and not be traced back. Everyone with a little knowledge about PCR can make a PCR look exactly the way they want it to look. That's why replication is the gold standard in science. Will other scientists come to the same results when they perform a published experiment in their own lab?
- genewitch 2y ago> Will other scientists come to the same results when they perform a published experiment in their own lab? Betteridge says "no" - https://www.nature.com/articles/533452a https://www.nature.com/articles/533452a for instance...
- cge 2y ago>That's why replication is the gold standard in science. Will other scientists come to the same results when they perform a published experiment in their own lab? I feel like it's worth a reminder to those reading this that replication isn't just about preventing fraud. I've personally seen far fewer examples of fraud than I have cases where difficulty reproducing results led to the discovery of considerations affecting the experiment that happened to present in the original experiment, but that the original researchers might not have thought of, or thought significant.