If every request is quick, you can easily re-use connections, file handles, threads, etc. If requests are slow, you will often need to spin up new connections,

If every request is quick, you can easily re-use connections, file handles, threads, etc. If requests are slow, you will often need to spin up new connections, as you don't want to wait for the response that might take hundreds of milliseconds. But I did start by saying it's not important. It's a small difference, unless you hit a connection limit.