I work in neurotech/sleeptech and work with Alzheimer's researchers. This is sensationalist and one-sided. Alzheimer's is the most common form of dementia, an

I work in neurotech/sleeptech and work with Alzheimer's researchers. This is sensationalist and one-sided. Alzheimer's is the most common form of dementia, and it is not clearly understood. It is potentially the most common form because it is not understood and there are many, myself among them, who believe that multiple different diseases are being assigned a single title because we don't understand the disease enough. This isn't to say the Amyloid hypothesis is correct, it may be correct in a number of cases, but the Type 3 Diabetes may also be correct. The Amyloid Hypothesis has not been disproven. Yes, misrepresented data in a few studies have significantly put into question the reliability, however hundreds of other not "doctored" studies have shown the hypothesis holds significant promise. The pharmaceutical companies did not make up the format of the disease in order to sell drugs, and the current drugs are not very effective, but that doesn't mean the theory is wrong. Just because amyloid build up is a marker of the disease does not mean that removing this metabolic waste would reverse the disease. That's like saying blowing your nose would cure the common cold. In the case of AD, the suspicion is that the Amyloid/Tau build up damages the neurons ability to signal within the brain, like a blockage in a pipe that causes the pipe to break. Removing the blockage does not repair the pipe. So why bother removing it at all? A researcher we work with has posited a theory (which is fairly new, but I'm not sure she is the first) that amyloid build up reduces the power of delta slow waves, and the related glymphatic flushing of metabolic waste. This is why the drugs might be valuable (I'll say might be, rather than are), increasing the removal of waste slows further progression of the disease. Having said that, there is a point in time where slowing progression is just lengthening time in poor health, and is not valuable, but prior to that, it can be valuable (I'll leave it up to individuals to decide what is right for them or their family members). We've been developing slow-wave enhancement technology at Affectable Sleep [1] for the last 5 years, and similar tech has shown early promise in people with AD [2] as well as potential preventative in elderly people [3]. [1] https://affectablesleep.com https://affectablesleep.com [2] https://pubmed.ncbi.nlm.nih.gov/39048400/ https://pubmed.ncbi.nlm.nih.gov/39048400/ [3] https://academic.oup.com/ageing/article/52/12/afad228/7503302 https://academic.oup.com/ageing/article/52/12/afad228/750330...